Tegumental alterations of adult Schistosoma japonicum harbored in mice treated with a single oral dose of mefloquine.

Objective: To observe the effect of mefloquine on the tegument of adult Schistosoma japonicum harbored in mice.

Methods: Twelve mice were each infected with 60-80 S. japonicum cercariae.

Effect of artemether on the tegument of adult Schistosoma haematobium recovered from mice.

Objective: To assess the effect of artemether on the tegument of adult Schistosoma haematobium harbored in mice.

Methods: Ten mice were infected subcutaneously with 100-120 S. haematobium cercariae each.

Ultrastructural alterations of adult schistosoma haematobium harbored in mice following artemether administration.

Objective: To perform a temporal examination of ultrastructural alterations in adult Schistosoma haematobium due to artemether.

Methods: Eight mice infected with 100-120 S. haematobium cercariae for 81 days were treated intragastrically with 400 mg/kg artemether.

Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). II. Morphological development of the adult and its comparison with humans.

Through 100 passages, the human hookworm Necator americanus was adapted to the golden hamster, Mesocricetus auratus, without either the requirement for exogenous steroids or other immunosuppressive agents, nor the requirement to infect hamsters as pups. Adult N. americanus recovered from infected hamsters were morphologically similar to those from infected humans in Sichuan Province, China, although they were smaller and the females produced fewer eggs.