Objective: To evaluate the association between the BNT162b2 (Pfizer-BioNTech) coronavirus disease vaccine and new-onset anterior uveitis.
Methods: A retrospective case control study of patients admitted and diagnosed with new-onset acute anterior uveitis, and matched controls admitted for other reasons (1:3 ratio), was completed. Rates of exposure to the BNT162b2 vaccine were compared between groups, and odds ratios for exposure to the vaccine were calculated.
Background: Onychoschizia is characterized by distal nail plate splitting. Several therapeutic approaches exist, most of which are based on case reports or small non-comparative case series.
Objective: To evaluate safety and efficacy of oral biotin and pyridoxine for treating onychoschizia.
Background: Seborrheic dermatitis (SD) is a common, chronic inflammatory skin disease with limited understanding of its pathophysiology. Molecular profiling has been limited by invasiveness of sampling methods.
Objective: To analyze the molecular skin profile of adult patients with SD using tape strips.
We find the comment on the article titled "Diabetic Foot and Fungal Infections: Etiology and Management from a Dermatologic Perspective" informative and wish to thank the authors for their added insight on this complex topic [...
View Article and Find Full Text PDFPurpose: To evaluate the accuracy of several intraocular lens (IOL) formulas for patients with endothelial dystrophy (ED) without edema treated with cataract surgery alone.
Setting: 1 academic, tertiary referral center.
Design: Comparative retrospective cohort study.
Purpose: To evaluate and quantify variation of biometric parameters - axial length (AL), anterior chamber depth (ACD), central corneal thickness (CCT) and white-to-white (WTW).
Methods: A population-based retrospective cohort study was performed on patients who underwent a biometry test prior to cataract surgery using the IOL Master 700 (Carl Zeiss Meditec, Jena, Germany) between the years 2017-2021. Differences in these parameters were evaluated between scans executed at different times of the day.
Purpose: To compare the outcomes of anterior chamber intraocular lens (AC-IOL) implantation versus the four-flanged scleral fixation technique in eyes with loss of capsular support during routine cataract surgery.
Methods: This was a retrospective cohort study of all patients in whom an IOL was implanted either during or after short-term aphakia due to loss of capsular and sulcus support in a routine cataract surgery with at least 6 months of follow-up time between 2015 and 2023 in a tertiary medical center in Israel. Two different IOL implantation techniques were compared: the implantation of an angle-supported ACIOL and four-flanged scleral fixation.
Introduction: There is an increasing number of reports of infections. This species is usually poorly responsive to terbinafine.
Areas Covered: A literature search was conducted in May 2024.
Introduction: Terbinafine is considered the gold standard for treating skin fungal infections and onychomycosis. However, recent reports suggest that dermatophytes are developing resistance to terbinafine and the other traditional antifungal agents, itraconazole and fluconazole. When there is resistance to terbinafine, itraconazole or fluconazole, or when these agents cannot used, for example, due to potential drug interactions with the patient's current medications, clinicians may need to consider off-label use of new generation azoles, such as voriconazole, posaconazole, fosravuconazole, or oteseconazole.
View Article and Find Full Text PDFIntroduction: The importance of myopia management lies in the desire to minimize the potential ocular risks that increase with high myopia.
Aims: To assess the decrease in myopia progression using topical low dose atropine combined with peripheral blur contact lenses (CL).
Methods: This retrospective review study included 25 children between the ages of 8.
Introduction: The global spread of Trichophyton indotineae presents a pressing challenge in dermatophytosis management. This systematic review explores the current landscape of T. indotineae infections, emphasizing resistance patterns, susceptibility testing, mutational analysis, and management strategies.
View Article and Find Full Text PDFPurpose: To measure and compare the inter-examiner reproducibility of manifest refraction in patients with keratoconus.
Design: Prospective, inter-examiner reliability analysis comparing cases and controls.
Methods: Patients with keratoconus (KC) and healthy subjects had undergone manifest refraction by the same 2 skilled optometrists; each was masked to the refraction of the other, on the same day.
Introduction: Lichen planopilaris (LPP) is a common type of primary cicatricial alopecia. Previous studies focused on the epidemiology, clinical characteristics, and treatment of LPP. A lack of knowledge regarding LPP outcomes and prognostic factors remained.
View Article and Find Full Text PDFIndividuals with psoriatic nails often have a lower quality of life relative to their counterparts with healthy nails. Methotrexate (MTX), an anti-neoplastic agent, is a longstanding treatment option for nail psoriasis. In the current study, we compared the effects of MTX to that of a corticosteroid, namely, methylprednisolone acetate (i.
View Article and Find Full Text PDFExpert Opin Pharmacother
February 2024
Introduction: Treating alopecia can be challenging. The available treatments are topical minoxidil, low-dose oral minoxidil (LDOM), and 5-α reductase inhibitors like finasteride and dutasteride. Only topical minoxidil and finasteride 1 mg daily are FDA-approved, while the rest are used off-label.
View Article and Find Full Text PDFObjective: It is accepted that ocular parameters are more correlated with the fellow eye. This poses a challenge in ophthalmic research. There is a relative scarcity of data concerning the extent of correlation.
View Article and Find Full Text PDFPurpose: The purpose of this study is to assess the diagnostic accuracy of ChatGPT in the field of ophthalmology.
Methods: This is a retrospective cohort study conducted in one academic tertiary medical center. We reviewed data of patients admitted to the ophthalmology department from 06/2022 to 01/2023.
Purpose: The aim of the study was to evaluate the efficacy and safety of quantum molecular resonance in the treatment of dry eye disease.
Methods: This study was a double-blind randomized control trial in 1 academic medical center, for 2 years. Participants received treatment or a placebo with the Rexon-Eye device, once per week for 4 weeks.
Background: Atopic dermatitis (AD) is one of the most common inflammatory skin diseases. It is associated with significant itch and impaired quality of life. Systemic treatments are efficient but associated with side effects.
View Article and Find Full Text PDFPurpose: To evaluate the risk of a retinal redetachment in women after vaginal delivery versus cesarean delivery.
Methods: Retrospective cohort analysis of patients diagnosed with retinal detachment (RD) who had later delivered in one tertiary medical center. Recurrence rates of RD were obtained from medical charts.