Adherence to antiretrovirals among US women during and after pregnancy.

Background: Antiretrovirals (ARVs) are recommended for maternal health and to reduce HIV-1 mother-to-child transmission, but suboptimal adherence can counteract its benefits.

Objectives: To describe antepartum and postpartum adherence to ARV regimens and factors associated with adherence.

Methods: We assessed adherence rates among subjects enrolled in Pediatric AIDS Clinical Trials Group Protocol 1,025 from August 2002 to July 2005 on tablet formulations with at least one self-report adherence assessment.