Synopsis of recent research by authors named "Shelley P Honnold"
Shelley P Honnold's research primarily focuses on the pathogenesis and immunological responses to various encephalitic alphaviruses, particularly Eastern equine encephalitis virus (EEEV) and Venezuelan equine encephalitis virus (VEEV), exploring effective vaccine candidates and therapeutic interventions. !*
-
Significant findings include the development of a trivalent virus-like particle vaccine that demonstrated efficacy in nonhuman primates, alongside studies revealing persistent viral replication in asymptomatic Ebola virus-infected monkeys, contributing to the understanding of viral persistence and immune response. !*
-
Honnold's work also emphasizes the limitations of existing animal models, such as the Syrian hamster, in accurately reflecting human-like diseases caused by these viruses, thus advocating for improved models and strategies for vaccine development and testing. !*