Tobacco dependence treatment for hospitalized smokers: a randomized, controlled, pilot trial using varenicline.

Objective: The hospital can be an important opportunity for smoking cessation interventions. This is the first randomized, double-blinded, placebo-controlled pilot trial utilizing varenicline and post-discharge, in-person behavioral treatment for hospitalized smokers.

Method: Seventy-nine smokers admitted to a university-based hospital with various diagnoses were enrolled from 2007 to 2009.

Triple-combination pharmacotherapy for medically ill smokers: a randomized trial.

Background: Smokers with medical illnesses are at particular risk for complications caused by tobacco. Clinical trial data on the effectiveness of triple-combination pharmacotherapy for tobacco dependence treatment in these high-risk smokers are not available.

Objective: To evaluate extended duration of a triple-medication combination versus standard-duration therapy with the nicotine patch alone and 6-month abstinence rates in smokers with medical illnesses.