Publications by authors named "Shelia Dian Thomas"
Article Synopsis
- Glyphosate, especially in products like Roundup, is a widely used herbicide that may disrupt endocrine functions and exhibit cytotoxic effects, particularly in breast cancer (BC) cell lines.
- Research aimed to explore how Roundup and its component AMPA affect gene expression in ER+ (MCF-7) and ER- (MDA-MB-468) BC cell lines, revealing deregulation in critical pathways related to cell cycle and DNA repair.
- Results indicate that exposure to low concentrations of Roundup leads to harmful cellular changes, including increased reactive oxygen species and potential DNA damage, highlighting significant risks even at short exposure durations in breast cancer models.
