Publications by authors named "Shelby S Umphres"

Article Synopsis
  • Cardiovascular disease (CVD) is the leading global cause of death, with smoking being a major preventable risk factor; e-waterpipes are gaining popularity despite unknown health effects.
  • Researchers studied the impact of e-waterpipe exposure on mice, using a protocol that mimics real-life usage to assess its occlusive CVD effects.
  • Results showed that e-waterpipe exposure led to increased platelet activation and a prothrombotic phenotype in mice, suggesting potential cardiovascular risks associated with e-waterpipe use.
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Introduction: The use of e-cigarettes (ECs) has reached unprecedented levels, due to a variety of reasons, including the misconception regarding their safety. Thus, there have been efforts to characterize the effects of EC exposure, including in the context of thirdhand EC (THEC) on a host of disorders, such as cardiovascular disease (CVD).

Methods: To address this issue, we sought to characterize the effects of THEC on platelet function and thrombus formation, using a novel mouse exposure protocol that resembles real life scenarios.

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