Power Spectrum Consistency among Systems and Transducers.

Use of the reference phantom method for computing acoustic attenuation and backscatter is widespread. However, clinical application of these methods has been limited by the need to acquire reference phantom data. We determined that the data acquired from 11 transducers of the same model and five clinical ultrasound systems of the same model produce equivalent estimates of reference phantom power spectra.

Automatic CT-ultrasound registration for diagnostic imaging and image-guided intervention.

The fusion of tracked ultrasound with CT has benefits for a variety of clinical applications, however extensive manual effort is usually required for correct registration. We developed new methods that allow one to simulate medical ultrasound from CT in real-time, reproducing the majority of ultrasonic imaging effects. They are combined with a robust similarity measure that assesses the correlation of a combination of signals extracted from CT with ultrasound, without knowing the influence of each signal.

Full angle spatial compounding for improved replenishment analyses in contrast perfusion imaging: in vitro studies.

For contrast enhanced perfusion imaging semi-quantitative methods (such as the bolus-, replenishment- or depletion-method) are commonly used to analyze the dynamic changes in concentration of contrast agent induced by insonification. In order to apply these methods and to decrease artifacts from tissue nonlinearity, perfusion imaging is conducted using decreased transmit power. However, echo signals from deeper structures are often too weak to be successfully analyzed.

An ultrasound research interface for a clinical system.

Under a contract with the National Cancer Institute, we have developed a research interface to an ultrasound system. This ultrasound research interface (URI) is an optional feature providing several basic capabilities not normally available on a clinical scanner. The URI can store high-quality beamformed radio-frequency data to file for off-line processing.

An ultrasound research interface for a clinical system.

Under a contract with the National Cancer Institute, we have developed a research interface to an ultrasound system. This ultrasound research interface (URI) is an optional feature providing several basic capabilities not normally available on a clinical scanner. The URI can store high-quality beamformed radio-frequency data to file for off-line processing.