Publications by authors named "Shekhar Raj"

Historically, acquiring a reliable and accurate non-invasive fetal electrocardiogram has several significant challenges in both data acquisition and attenuation of maternal signals. These barriers include maternal physical/physiological parameters, hardware sensitivity, and the effectiveness of signal processing algorithms in separating maternal and fetal electrocardiograms. In this paper, we focus on the evaluation of signal-processing algorithms.

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Article Synopsis
  • Heart sound segmentation enhances AI auscultation decision support systems, addressing the decline in physical exam skills and reducing subjectivity in heart sound interpretation.
  • A new noise-robust segmentation algorithm was tested on two datasets, showing high accuracy in identifying heart sound boundaries and significantly faster performance than previous models.
  • The algorithm's effectiveness (87.4% success rate on the CNH dataset) improves the reliability of heart sound analysis, supporting advancements in cardiovascular AI research and clinical applications.
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Significance: Conventional ultrasound-guided vascular access procedures are challenging due to the need for anatomical understanding, precise needle manipulation, and hand-eye coordination. Recently, augmented reality (AR)-based guidance has emerged as an aid to improve procedural efficiency and potential outcomes. However, its application in pediatric vascular access has not been comprehensively evaluated.

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Background: Hypertension (HTN) has a genetic predisposition and it also impairs microcirculation, thereby, affecting the well vascularized structures like the brainstem and causing changes in Brainstem Auditory Evoked Potentials (BAEPs).

Purpose: To find out the usefulness of BAEPs as a screening tool in apparently healthy individuals with a family history of HTN.

Methods: One hundred and ten volunteers, aged 17 to 23 years, were enrolled in the study as participants with proper consent.

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Case: A 29-year-old young active man with ununited necrosed proximal fifth of scaphoid with chronic scapholunate ligament disruption was managed by excision of proximal pole fragment and interosseous scapholunate reconstruction using modified Brunelli triple ligament tenodesis technique with satisfying outcome at 6 months and return to sports instructor job by the end of 1 year.

Conclusion: Meticulous understanding and algorithmic itemwise approach of injury components can lead to optimal management of complex unstable wrist injuries such as scapholunate dissociation. To the best of our knowledge, this is the first report on excision of proximal pole of scaphoid coupled with scapholunate ligament reconstruction.

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Objective: Augmented reality devices are increasingly accepted in health care, though most applications involve education and pre-operative planning. A novel augmented reality ultrasound application, HoloUS, was developed for the Microsoft HoloLens 2 to project real-time ultrasound images directly into the user's field of view. In this work, we assessed the effect of using HoloUS on vascular access procedural outcomes.

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(1) Background: Mastery of auscultation can be challenging for many healthcare providers. Artificial intelligence (AI)-powered digital support is emerging as an aid to assist with the interpretation of auscultated sounds. A few AI-augmented digital stethoscopes exist but none are dedicated to pediatrics.

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Digital stethoscopes can enable the development of integrated artificial intelligence (AI) systems that can remove the subjectivity of manual auscultation, improve diagnostic accuracy, and compensate for diminishing auscultatory skills. Developing scalable AI systems can be challenging, especially when acquisition devices differ and thus introduce sensor bias. To address this issue, a precise knowledge of these differences, i.

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Background: Still's murmur is the most prevalent innocent heart murmur of childhood. Auscultation is the primary clinical tool to identify this murmur as innocent. Whereas pediatric cardiologists routinely perform this task, primary care providers are less successful in distinguishing Still's murmur from the murmurs of true heart disease.

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Background: Quality of cardiopulmonary resuscitation (CPR) contributes significantly to outcomes. Key determinants of CPR quality pertaining to chest compressions are compression rate, compression depth, duration of interruptions, and chest recoil. Several studies have demonstrated that real-time audiovisual feedback improves CPR quality.

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Background: India's dominant private healthcare sector is the destination for 60-85% of initial tuberculosis care-seeking. The COVID-19 pandemic in India drastically affected TB case notifications in the first half of 2020. In this survey, we assessed the impact of the first wave of COVID-19 in India on private providers, and changes they adopted in their practice due to the pandemic.

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Introduction: Chylothorax, a relatively rare congenital heart disease early postoperative complication, is occurring more frequently due to complexity of cardiac surgeries.

Presentation Of Case: We present a 9-month-old boy who had hypoplastic left heart (HLH) syndrome with interrupted inferior vena cava (IVC) and bilateral superior vena cava (SVC) palliated with left sided modified Blalock-Taussig (MBT) shunt during neonatal period and second stage palliation with left sided bidirectional glen (BDG) procedure and right sided Kawashima procedure develop bilateral chylothorax two weeks after discharge.

Discussion: This is the first reported case in the literature of a patient who developed chylothorax with relatively low Fontan systemic venous pressures after a Kawashima procedure.

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Epileptic focal seizures can be localized in the brain using tracer injections during or immediately after the incidence of a seizure. A real-time automated seizure detection system with minimal latency can help time the injection properly to find the seizure origin accurately. Reliable real-time seizure detection systems have not been clinically reported yet.

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Objectives: Timely thrombolysis of ischaemic stroke improves functional recovery, yet its delivery nationally is challenging due to shortages in the stroke specialist workforce and large geographical areas. One solution is remote stroke specialist input to regional centres via telemedicine. This study evaluates the usage and key metrics of performance of the East of England Stroke Telemedicine Partnership-the largest telestroke service in the UK-in providing hyperacute stroke care.

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Purpose: Microsoft HoloLens is a pair of augmented reality (AR) smart glasses that could improve the intraprocedural visualization of ultrasound-guided procedures. With the wearable HoloLens headset, an ultrasound image can be virtually rendered and registered with the ultrasound transducer and placed directly in the practitioner's field of view.

Methods: A custom application, called HoloUS, was developed using the HoloLens and a portable ultrasound machine connected through a wireless network.

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When preprocedural images are overlaid on intraprocedural images, interventional procedures benefit in that more structures are revealed in intraprocedural imaging. However, image artifacts, respiratory motion, and challenging scenarios could limit the accuracy of multimodality image registration necessary before image overlay. Ensuring the accuracy of registration during interventional procedures is therefore critically important.

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The purpose of this work was to develop a new method of tracking a laparoscopic ultrasound (LUS) transducer in laparoscopic video by combining the hardware [e.g., electromagnetic (EM)] and the computer vision-based (e.

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Aim: To analyze racial disparities in Coronavirus disease (COVID-19) cases in the United States of America and discuss possible reasons behind this inequality.

Subject And Methods: We obtained estimated case counts of African-American, Caucasian, Native American, Asian and Hispanic individuals with coronavirus disease (COVID-19)infection through May 5, 2020, from publicly available data on state departments of health websites. We calculated race-specific fractions as the percentage of the total population and analyzed the reasons behind this disparity.

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Article Synopsis
  • The study investigates the effectiveness of procalcitonin as a diagnostic tool for childhood bacterial pneumonia, which is a significant health concern.
  • It analyzed data from 25 studies involving nearly 2,900 patients, finding that procalcitonin showed moderate sensitivity (64%) and specificity (72%) for diagnosing bacterial pneumonia.
  • The authors suggest using procalcitonin alongside other diagnostic methods, as it isn't strong enough to be relied on alone, particularly since elevated levels did not significantly correlate with bacterial pneumonia cases.
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Purpose: For laparoscopic ablation to be successful, accurate placement of the needle to the tumor is essential. Laparoscopic ultrasound is an essential tool to guide needle placement, but the ultrasound image is generally presented separately from the laparoscopic image. We aim to evaluate an augmented reality (AR) system which combines laparoscopic ultrasound image, laparoscope video, and the needle trajectory in a unified view.

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Surgical tool tracking has a variety of applications in different surgical scenarios. Electromagnetic (EM) tracking can be utilised for tool tracking, but the accuracy is often limited by magnetic interference. Vision-based methods have also been suggested; however, tracking robustness is limited by specular reflection, occlusions, and blurriness observed in the endoscopic image.

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Tracking the location and orientation of a laparoscopic ultrasound (LUS) transducer is a prerequisite in many surgical visualization and navigation applications. Electromagnetic (EM) tracking is a preferred method to track an LUS transducer with an articulating imaging tip. The conventional approach to integrating EM tracking with LUS is to attach an EM sensor on the outer surface of the imaging tip (external setup), which is not ideal for routine clinical use.

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Introduction: Intraoperative imaging, such as ultrasound, provides subsurface anatomical information not seen by standard laparoscopy. Currently, information from the two modalities may only be integrated in the surgeon's mind, an often distracting and inefficient task. The desire to improve intraoperative efficiency has guided the development of a novel, augmented reality (AR) laparoscopic system that integrates, in real time, laparoscopic ultrasound (LUS) images with the laparoscopic video.

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