Publications by authors named "Sheiner E"

Children with specific psychophysiological profiles may be more strongly affected by adverse environmental experiences. Guided by a biopsychosocial perspective, we examined whether infant respiratory sinus arrhythmia (RSA), an index of parasympathetic functioning, moderates the associations between paternal postpartum depression (PPD) symptoms and infants' observed empathy-related responses. Participants were 142 families with infants (51% female) assessed at two time points.

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Article Synopsis
  • The study investigates how prenatal exposure to heavy metals (Lead, arsenic, cadmium, selenium) relates to adverse pregnancy outcomes, particularly focusing on differences between low-risk and high-risk groups of women with varying preterm birth histories.
  • 404 women participated, and their blood metal levels were measured, showing significant differences in concentration between low-risk and high-risk groups, with low-risk having higher levels of these metals.
  • Despite the findings of elevated metal levels, the study found no significant correlation between these metals and negative pregnancy outcomes, indicating a need for more research to explore the effects of these metals on pregnancy.
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The human body has the ability to adapt to changing circumstances, and mobilizes various biological systems in order to do so. When exposed to stressful conditions, the endocrine, nervous, and immune systems come together to aid in maintaining homeostasis; however, during periods of chronic stress, these systems can become maladaptive and lead to long-term detrimental health outcomes. Amongst the lingering effects associated with chronic stress exposure, increasingly, studies are identifying a link to adverse pregnancy and neonatal outcomes.

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Objective: To examine the impact of war conditions on maternal mental health postpartum outcomes, specifically depression and anxiety, as well as on maternal-infant bonding (MIB).

Study Design: A prospective cohort study was performed on women who gave birth in a tertiary medical center during (October-November 2023) and before (March-May 2020) the Israel-Hamas War. All participants completed validated self-reported questionnaires: The Edinburgh Postnatal Depression Scale (EPDS ≥ 10), State-Trait Anxiety Inventory (STAI > 39) and the Postpartum Bonding Questionnaire (PBQ ≥ 26).

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Exposure to maternal depressive symptoms (MDS) may have a pertinent role in shaping children's emotional development. However, little is known about how these processes emerge in the early postpartum period. The current study examined the direct and interactive associations between MDS and cry-processing cognitions in the prediction of infant negative emotionality and affective concern.

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Purpose: Postpartum depression (PPD) affects 10-15% of postpartum women with increased risk among women with trauma history. The purpose of this study was to investigate the relationship between adverse life events and postpartum depressive symptoms among Bedouin and Jewish women.

Methods: A cross-sectional study was performed in a tertiary hospital in the southern district of Israel on women with singleton deliveries between November 2021 and March 2022.

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Objectives: Small for gestational age (SGA) singletons are at increased risk for neurodevelopmental abnormalities. Scarce data exist regarding the long-term implications of SGA in twins. We opted to study the association between SGA of one twin and long-term neurologic related morbidity in dichorionic diamniotic twins.

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Objective: With inconsistencies regarding the possible effect of hyperemesis gravidarum on the course of pregnancy, this research aimed to study the association between hyperemesis gravidarum and pregnancy outcomes, while also addressing the trimester of diagnosis and severity.

Methods: A retrospective cohort study was performed, including all singleton deliveries of mothers from the largest health maintenance organization in the country, in a single tertiary hospital between 1991 and 2021. The incidence of adverse pregnancy outcomes was compared between pregnancies with and without hyperemesis gravidarum diagnosis.

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Purpose: Techniques of medically assisted reproduction interact with the embryo at crucial developmental stages, yet their impact on the fetus and subsequent child's health remains unclear. Given rising infertility rates and more frequent use of fertility treatments, we aimed to investigate if these methods heighten the risk of autism spectrum disorder (ASD) in children.

Methods: A population-based cohort study was conducted at Soroka University Medical Center, a tertiary referral hospital, encompassing singleton births.

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Objective: Fetal growth restriction (FGR) is a major determinant of adverse short- and long-term perinatal outcomes. The current definition of FGR (estimated fetal weight measurement < 10th percentile) may lead, at times, to a false diagnosis of fetuses that are eventually born appropriate for gestational age (AGA). Our objective was to investigate the potential association between a misdiagnosis of antepartum fetal growth restriction and long-term neurological outcomes in offspring.

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Purpose: To investigate differences in reproductive outcomes among patients before and following ovarian torsion.

Study Design: In this retrospective cohort study, we investigated the reproductive outcomes of patients who underwent surgery for ovarian torsion between 1988 and 2015 in a tertiary medical center. Data on deliveries before and after ovarian torsion were compared.

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Objective: An ultrasound-based diagnosis implies that some fetuses suspected to be growth-restricted (FGR) are discovered at birth to be appropriately grown (appropriate for gestational age [AGA] birth weight, between the 10th and 90th percentile). These fetuses may thus be exposed to unnecessary medical interventions, including early labor induction. In this study, we have evaluated the long-term respiratory health of offspring misclassified as FGR.

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Article Synopsis
  • The rise in chronic hypertension among women of reproductive age is linked to delayed childbearing and significantly increases the risk of preeclampsia and other placenta-mediated complications during pregnancy.
  • A comprehensive study at Soroka University Medical Center analyzed data from over 356,000 deliveries to compare complications such as fetal growth restriction and preterm delivery between mothers with and without chronic hypertension.
  • The findings revealed that chronic hypertension is independently associated with higher rates of these complications, indicating the need for early detection and careful monitoring in pregnant women, especially those of advanced maternal age.
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: Chorioamnionitis during labor exposes the fetus to an intrauterine state that may alter the future immune response and may expose the offspring to future susceptibility to infectious disease. We evaluated the long-term pediatric infectious morbidity of children born at term to mothers who have chorioamnionitis during labor. This was a population-based cohort analysis including only term singleton deliveries at a regional tertiary hospital between the years 1991 and 2021.

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Objective: To identify risk factors for developing early postpartum hemorrhage (PPH) and to examine whether risk factors vary according to severity and mode of delivery.

Methods: A population-based cohort study was conducted in which all deliveries at a tertiary medical center were included. Risk factors for developing early PPH were compared based on the severity of bleeding as well as the mode of delivery.

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Purpose: An ancient description of the competition between twins for first breath is found in the biblical story of Jacob and Esau (Genesis 25:26) when Jacob pulled his older brother's heel in the hope of becoming firstborn but to no avail. In this study, we sought to evaluate the short and long-term outcomes of twin pairs, comparing between the second- and first-born twin.

Methods: A population-based cohort study, including dichorionic twin deliveries occurring between the years 1991 and 2021 at Soroka University Medical Center.

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Background: Lung maldevelopment due to in-utero events may potentially cause respiratory morbidity during childhood. Maternal nutritional status during pregnancy is critical for lung development. This study is contributing to the understanding of the interplay between maternal nutrition status during pregnancy, fetal lung development and the risk for respiratory diseases in early life.

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Purpose: To investigate perinatal outcomes and long-term infectious morbidity in children of mothers with familial Mediterranean fever (FMF).

Methods: A population-based cohort study comparing perinatal outcomes and long-term infectious morbidity of offspring of mothers with and without FMF was conducted. All singleton deliveries between the years 1991-2021 in a tertiary medical center were included.

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Objective: The main risk factor for preterm delivery (PTD; <37 gestational weeks) is having a history of PTD. The aim of this research was to compare the risk for recurrent PTD following twin versus singleton gestation PTD.

Methods: A retrospective population-based cohort study was performed, including all women who had two consecutive pregnancies, the first of which ended with PTD.

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Background: Controversy exists regarding the association between autism spectrum disorder (ASD) in children whose mother had labour epidural analgesia for their birth, as the few existing investigations have reported mixed findings.

Objective: This study aims to evaluate the possibility of an association in our heterogeneous population.

Design: A retrospective population-based cohort study.

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Purpose: The association between birth order and adverse perinatal outcomes has been well studied in twin pregnancies. However, little is known about the differences in immediate perinatal outcomes as well as long-term hospitalization of the offspring in triplet pregnancies according to their birth order. As such, we aimed to assess the differences in immediate perinatal outcomes and long-term hospitalizations among triplets by their birth order.

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Background: There are limited data regarding the perinatal consequences of maternal syncope during pregnancy, and even less is known about the potential long-term effect on offspring health.

Objective: This study aimed to examine perinatal outcomes as well as long-term offspring neurologic morbidity associated with prenatal maternal syncope, and the possible differential effect by trimester of first syncope episode.

Study Design: A retrospective cohort study was conducted, including all singleton deliveries occurring between 1991 and 2021 at a large tertiary medical center.

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Purpose: The present study aims to investigate the association between emotion regulation difficulties and pain perception during the immediate postpartum period.

Methods: A cross-sectional study was performed in women during the immediate postpartum period. Women completed the Difficulties in Emotion Regulation Scale (DERS) questionnaire to measure difficulties in emotion regulation.

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Background: Offspring born via cesarean delivery (CD) may be more prone to develope long-term respiratory diseases, compared to those delivered vaginally (VD). In this study, we compared the rates of respiratory diseases between first twins VD and second twins delivered via CD.

Methods: This was a retrospective database study.

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