The proxy dilemma: Informed consent in paediatric clinical research - a case study of Thailand.

Informed consent is an essential requirement for the ethical conduct of research. It is also a necessary requirement for the lawful conduct of research. Informed consent provides a legal basis to enrol human subjects in clinical research.

Ethics, economics, and the use of primaquine to reduce falciparum malaria transmission in asymptomatic populations.

Yoel Lubell and colleagues consider ethical and economic perspectives on mass drug administration of primaquine to limit transmission of P. falciparum malaria. Please see later in the article for the Editors' Summary.