A new model for repair of the Achilles tendon in the rat.

The Sprague-Dawley rat is an excellent model for studies of Achilles tendon repair. Most researchers use a modification of the Kessler technique for suture repair of the Achilles tendon in rats. While this technique provides adequate strength, early mobilization is not recommended.

The effects of deferoxamine on the survival of free flaps using the adult male rat as a model - biomed 2009.

A free flap is defined as tissue that is moved to a new location along with its own inherent blood supply. The ability to transfer tissue based on microvascular anastomoses has created a revolution in reconstructive surgery. However, secondary ischemia is a serious problem for the survival of a free flap after transfer.

Connective tissue growth factor (ctgf) expression in the tenosynovium of patients with carpal tunnel syndrome - biomed 2009.

Connective Tissue Growth Factor (CTGF) expression has been identified in a wide variety of fibrotic disorders; however, the expression of CTGF in carpal tunnel syndrome (CTS) has not yet been described in the literature. Both inflammatory and fibrotic etiologies have been implicated in the pathogenesis of CTS, with current evidence favoring an emphasis on a non-inflammatory fibrosis pathophysiological picture. Our objective was to identify whether CTGF is expressed in the tenosynovium of patients with CTS.

Malunions of the finger metacarpals and phalanges.

Many malunions of the finger metacarpals are mild and do not require or justify operative intervention. Early recreation of the fracture or osteotomy is more likely to be rewarded with favorable results than late operation. Rotational malunions of the metacarpals or proximal phalanges may be treated by transverse extra-articular transverse or step-cut osteotomies at or proximal to the malunion site.

Hand fractures and dislocations in the developing skeleton.

Management of children's fractures requires a thorough knowledge of the developing skeleton, with recognition of the injury present and its potential course based on mechanism and anatomy, a dedication to complete and repeated clinical and radiologic examinations, and a willingness to intercede if unacceptable angulation or any rotation occurs in the course of treatment. The ability to remodel follows a well-defined course and may be anticipated within certain margins, but expectations of this ability should not be overemphasized or even contemplated outside the direction of joint motion. Growth arrest following injury, although a real concern, remains rare.

Evaluation of fructose 1,6 diphosphate for salvage of ischemic gracilis flaps in rats.

Fructose 1, 6 diphosphate (FDP), a metabolic intermediate, provides an alternative mechanism to circumvent the rate-limiting step in the Kreb's cycle. This agent has been observed to prevent the effects of ischemia on heart tissue and kidney function and the effects of endotoxic shock. It has been shown conclusively to minimize the adverse effects of ischemia-reperfusion injury in experimental pedicled skin flaps in animals.

Prevalence of anatomic variations encountered in elective carpal tunnel release.

Purpose: To determine the prevalence of aberrant or unexpected anatomic structures within one surgeon's elective experience of carpal tunnel releases and their association with pathologic compression.

Methods: A total of 31 anomalies of median nerve, muscle, and tendon, median artery persistence, and ulnar nerve were documented in 30 hands during the course of 526 elective carpal tunnel releases in one surgeon's practice. The data collected were reviewed retrospectively.

Fracture fixation in the mutilated hand.

Early anatomic (or near anatomic; lingers do not impinge or overlap during flexion or extension) stable fracture fixation provides the foundation for successful wound management and for the repair, reconstruction, and healing of all damaged tissues in a mutilating hand injury. It also plays an instrumental role in pain control and affords an optimal opportunity for timely and favorable rehabilitation of and recovery from mutilating injuries of the hand. Kirschner or other wiring systems or mini external fixators may be used for simple fractures, in children, when rapid fracture fixation is necessary, and for provisional fracture fixation.