Publications by authors named "Sheila Klassen"

Article Synopsis
  • The document addresses corrections made to a previously published article identified by DOI: 10.5334/gh.1313.
  • It highlights specific errors or omissions that needed rectification to ensure accuracy and clarity in the research.
  • The corrections aim to enhance the reliability of the findings and conclusions presented in the original article.
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Article Synopsis
  • Rheumatic and congenital heart diseases, along with cardiomyopathies and hypertensive heart disease, lead to significant health issues and fatalities in low- and lower middle-income countries (LLMICs), impacting the poorest populations.
  • Access to advanced cardiac care is limited, primarily concentrated in urban areas, creating a gap in healthcare for rural communities due to shortages of diagnostics, medications, and trained personnel.
  • The Package of Essential NCD Interventions - Plus (PEN-Plus) aims to improve access to cardiac care in these regions by decentralizing services, and a coalition of global cardiac organizations is collaborating to implement effective strategies for managing severe cardiac diseases in high-poverty settings.
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Article Synopsis
  • - The study explores the use of peer support interventions for managing cardiometabolic diseases, like type 2 diabetes, in low- and middle-income countries, where the effectiveness is not well established.
  • - A scoping review analyzed 28 studies, with the majority from Asia, and found that while peer support is beneficial for emotional coping and disease management, definitions and implementations vary widely.
  • - The findings suggest a need for standardized definitions of peer support and continuous evaluation of programs to improve future research and effectiveness in managing these diseases in LMICs.
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Background: Cardiovascular disease (CVD) is a major cause of death in Malawi. In rural districts, heart failure (HF) care is limited and provided by non-physicians. The causes and patient outcomes of HF in rural Africa are largely unknown.

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Unlabelled: Guyana is one of the poorest countries in South America, with the highest rate of cardiovascular mortality on the continent. As is the case in many low- and middle-income countries, cardiovascular care is available through the private sector but is not accessible to much of the urban and rural poor. We present the 10-year experience of the Guyana Program to Advance Cardiac Care (GPACC), an academic partnership aiming to provide high-quality, equitable cardiovascular care in Georgetown's only public hospital.

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• RHD is a common cause of heart failure in sub-Saharan Africa. • Task shifting by training rural providers in POCUS improves cardiac imaging access. • POCUS in low-resource settings can determine presence of structural heart disease.

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Background: Despite declines in deaths from rheumatic heart disease (RHD) in Africa over the past 30 years, it remains a major cause of cardiovascular morbidity and mortality on the continent. We present an investment case for interventions to prevent and manage RHD in the African Union (AU).

Methods: We created a cohort state-transition model to estimate key outcomes in the disease process, including cases of pharyngitis from group A streptococcus, episodes of acute rheumatic fever (ARF), cases of RHD, heart failure, and deaths.

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This case report describes a 55-year-old male who presented with acute Type A aortic dissection. He underwent emergent surgical repair, and his intraoperative transesophageal echocardiography revealed a quadricuspid aortic valve. His aortic root measured 45 mm.

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• Aortopulmonary fistulas in IE are a cause of aorta–to–pulmonary connections. • Other causes include PDA and ruptured sinus of Valsalva aneurysm. • Continuous flow is seen in modified views of the pulmonary artery.

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Objective: Oral anticoagulation (OAC) reduces stroke risk in patients with atrial fibrillation (AF) or atrial flutter (AFL). However, OAC initiation rates in patients discharged directly from the emergency department (ED) are low. We aimed to address this care gap by implementing a quality improvement intervention.

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Background: Guyana is a small developing country with a high burden of cardiovascular disease and extensive barriers to optimal care delivery. We investigated the effectiveness of a newly established multidisciplinary inpatient cardiology service in this setting.

Methods: We performed an interrupted time-series cohort study of heart failure (HF) patients admitted to the Georgetown Public Hospital Corporation from January to December 2015 and July 2016 to December 2017.

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Aortic stenosis (AS) is the most common valvular disease in the elderly and is associated with poor outcomes. Transcatheter aortic valve replacement (TAVR) is an alternative to surgical aortic valve replacement (SAVR) in high-risk patients. Herein, we describe the gender-related differences in baseline characteristics and pathophysiologic response to severe AS, imaging considerations unique to females, and short- and long-term outcomes after TAVR.

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Atrial fibrillation and atrial flutter (AF/AFL) are associated with an increased risk of stroke and systemic embolism. However, many patients are not started on guideline-recommended oral anticoagulation (OAC). We determined factors associated with initiation of OAC in eligible patients presenting to emergency departments.

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Echocardiography plays an important role in the assessment of valvular aortic stenosis. Updated recommendations focusing on a stepwise approach to evaluating aortic stenosis have recently been published by the European Association of Cardiovascular Imaging and the American Society of Echocardiography. This review uses illustrative cases to demonstrate technical aspects of aortic stenosis assessment and use of the new proposed classification scheme for aortic stenosis.

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