Publications by authors named "Sheila Alcaine"

Article Synopsis
  • The research team developed a waist-worn accelerometry device to detect dyskinesia in Parkinson's disease patients during daily activities.
  • The study involved 13 symptomatic patients who wore the device and had their activities recorded on video while a physician assessed their dyskinesia using the Unified Dyskinesia Rating Scale (UDysRS).
  • Results showed a strong correlation (0.70) between the device's output and physician assessments, particularly a higher correlation (0.91) for specific body parts (trunk and legs) being monitored.
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Unlabelled: The treatment of Parkinson's disease (PD) with levodopa is very effective. However, over time, motor complications (MCs) appear, restricting the patient from leading a normal life. One of the most disabling MCs is ON-OFF fluctuations.

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Article Synopsis
  • Researchers developed a small monitoring device using accelerometers to detect motor fluctuations in Parkinson's patients by analyzing gait patterns.
  • 75 Parkinson's patients were studied while walking in both On and Off states, measuring their coordination with a wearable sensor and comparing results to the UPDRS-III motor section.
  • The algorithm showed moderate to good correlation with UPDRS-III scores, indicating it may serve as an effective tool for monitoring motor fluctuations in these patients.
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Inertial measurement units (IMUs) are devices used, among other fields, in health applications, since they are light, small and effective. More concretely, IMUs have been demonstrated to be useful in the monitoring of motor symptoms of Parkinson's disease (PD). In this sense, most of previous works have attempted to assess PD symptoms in controlled environments or short tests.

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Among Parkinson's disease (PD) symptoms, freezing of gait (FoG) is one of the most debilitating. To assess FoG, current clinical practice mostly employs repeated evaluations over weeks and months based on questionnaires, which may not accurately map the severity of this symptom. The use of a non-invasive system to monitor the activities of daily living (ADL) and the PD symptoms experienced by patients throughout the day could provide a more accurate and objective evaluation of FoG in order to better understand the evolution of the disease and allow for a more informed decision-making process in making adjustments to the patient's treatment plan.

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Background: After several years of treatment, patients with Parkinson's disease (PD) tend to have, as a side effect of the medication, dyskinesias. Close monitoring may benefit patients by enabling doctors to tailor a personalised medication regimen. Moreover, dyskinesia monitoring can help neurologists make more informed decisions in patient's care.

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Freezing of gait (FOG) is a common motor symptom of Parkinson's disease (PD), which presents itself as an inability to initiate or continue gait. This paper presents a method to monitor FOG episodes based only on acceleration measurements obtained from a waist-worn device. Three approximations of this method are tested.

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