Publications by authors named "Sheikh Mujeeb"

Background: Outcomes of patients with hypertrophic cardiomyopathy (HCM) following transcatheter aortic valve replacement (TAVR) remain largely unknown.

Objectives: This study sought to assess the clinical characteristics and outcomes of HCM patients following TAVR.

Methods: We queried the National Inpatient Sample from 2014 to 2018 for TAVR hospitalizations with and without HCM, creating a propensity-matched cohort to compare outcomes.

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Aims: Literature regarding outcomes associated with atrial fibrillation among cirrhosis patients who had left atrial appendage occlusion (LAAO) device procedure is limited. We aim to evaluate the in-hospital clinical outcomes and 30-day readmissions among LAAO with and without cirrhosis.

Methods And Results: We performed a retrospective study of all hospitalizations associated with the LAAO procedure, using the Nationwide Readmissions Database for the years 2016-19.

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Objective: Cardiac arrest can complicate infective endocarditis (IE) and is associated with significant in-hospital complications and mortality rates. We report the characteristics, outcomes, and readmission rates for IE patients with cardiac arrest in the United States.

Methods: We surveyed the Nationwide Readmission Database (NRD), a database designed to support national level readmission analyses, for patients admitted with IE and who had cardiac arrest during index admission between 2016 and 2019.

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Background: The literature on prevalence and outcomes of coronary artery aneurysm (CAA) in the United States (US) is limited.

Objective: To study the prevalence, outcomes, and trends of CAA.

Methods: Data from the national readmissions database (NRD) sample that constitutes 49.

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Article Synopsis
  • Surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) are common treatments for severe aortic stenosis (AS), but patients with hypertrophic cardiomyopathy (HCM) were not included in major studies comparing these methods.
  • A study analyzing data from 2016 to 2019 found that among HCM patients with severe AS, those who underwent TAVR had lower in-hospital mortality rates and fewer complications like bleeding and acute kidney injury compared to those who had SAVR.
  • TAVR also resulted in shorter hospital stays and fewer patients needing to be discharged to different facilities, while overall hospital costs remained similar between the two procedures.
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This study aimed to study group differences in patients presenting with ST-elevation myocardial infarction (STEMI) based on the presence or absence of associated coronary artery aneurysms (CAA). The cause-and-effect relationship between CAAs and STEMI is largely unknown. The Nationwide Readmission database was used to identify and study group differences of patients with STEMI and with and without CAA from 2014 to 2018.

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Background: The literature on the mortality and 30-day readmissions for acute heart failure and for acute myocardial infarction among renal-transplant recipients is limited.

Objective: To study the in-hospital mortality, cardiovascular complications, and 30-day readmissions among renal transplant recipients (RTRs).

Methods: Data from the national readmissions database sample, which constitutes 49.

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Background: Literature regarding trends for incidence and mortality of scleroderma renal crisis (SRC) in systemic sclerosis (SSc) within the United States (US) emergency departments (EDs) is limited.

Objective: To study the mortality of SRC among SSc patient encounters within the US EDs.

Methods: Data from the National Emergency Department Sample (NEDS) constitutes 20% sample of hospital-owned EDs and inpatient sample in the US were analyzed for SSc with and without SRC using ICD-9 codes.

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Background: Literature regarding trends in incidence and mortality of ST-elevation myocardial infarction (STEMI) in emergency departments (EDs) is limited.

Objective: To study the trends of incidence and mortality of STEMI.

Methods: Using the National Emergency Department Sample database in the United States, we identified all ED encounters for patients presenting with STEMI using International Classification of Diseases codes.

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Literature regarding recent trends, mortality outcomes of ST-elevation myocardial infarction (STEMI) in cardiac amyloidosis (CA) patients is limited.To study coronary interventions, and trends in prevalence and mortality outcomes among CA patients with STEMI.Data from the national readmissions database (NRD) sample that constitutes 49.

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Introduction: The majority of studies evaluating the effect of myocardial injury on the survival of COVID-19 patients have been performed outside of the United States (U.S.).

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Objective: To study coronary interventions and mortality among patients with ST-elevated myocardial infarction (STEMI) who were admitted with septic shock.

Methods: Data from the national emergency department sample (NEDS) that constitutes 20% sample of hospital-owned emergency departments in the United States was analyzed for the septic shock related visits from 2016 to 2018. Septic shock was defined by the ICD codes.

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Article Synopsis
  • STEMI hospitalizations in the U.S. decreased significantly from 421,043 in 2002 to 208,510 in 2016, with a higher rate observed in males, whites, and those with higher socioeconomic status.
  • The rate of primary percutaneous coronary intervention (PCI) for STEMI patients rose from 32.8% in 2002 to 67.8% in 2016, particularly benefiting males, urban patients, and those from higher SES backgrounds.
  • Despite the decline in hospitalizations, there was an increasing prevalence of comorbidities among STEMI patients, and females, rural communities, and low SES groups continue to be at higher risk, highlighting a need for targeted healthcare interventions
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Background: The literature on outcomes of ST-elevation myocardial infarction (STEMI) amongst kidney transplant recipients (KTR) is limited.

Objective: To study the outcomes of STEMI among KTR.

Methods: Data from the national readmissions database (NRD) sample that constitutes 49.

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Background: Literature regarding outcomes of cardiac arrest with associated NSTEMI is limited. We aim to study the predictors and survival outcomes of cardiac arrest patients presenting to the emergency department who were diagnosed with non-ST elevated myocardial infarction (NSTEMI).

Methods: Data from the nationwide emergency department sample (NEDS) that constitutes 20% sample of hospital-owned emergency departments in the United States was analyzed for the cardiac arrest related visits from 2009-2018.

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Background: The effects of cardiovascular comorbidities on outcomes in COVID-19 hospitalized patients has not been well studied.

Methods: This is a hospital-based study evaluating the effects of CVD on the outcomes in patients admitted with COVID-19. Clinical outcomes were studied in patients with and without CVD.

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Literature regarding etiology and trends of incidence of major thoracic vein thrombosis in the United States is limited. To study the causes, complications, in-hospital mortality rate, and trend in the incidence of major thoracic vein thrombosis which could have led to superior vena cava syndrome (SVCS) between 2010 and 2018. Data from the nationwide emergency department sample (NEDS) that constitutes 20% sample of hospital-owned emergency departments (ED) and in-patient sample in the United States were analyzed using diagnostic codes.

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Literature regarding recent trends and outcomes of acute new-onset heart failure (AHF) with preserved ejection fraction (AHFpEF) and reduced ejection fraction (AHFrEF) is limited. The objective of this study is to study the outcomes of AHFpEF and AHFrEF in the USA. Data from the National Readmissions Database (NRD) sample that constitutes 49.

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Scarce data exist on the prognostic impact of type 2 myocardial infarction (MI) in patients with AF. The Nationwide Readmission Database 2018 was queried for primary AF hospitalizations with and without type 2 MI. Complex samples multivariable logistic and linear regression models were used to determine the association between type 2 MI and outcomes (in-hospital mortality, index length of stay [LOS], hospital costs, discharge to nursing facility, and 30-day all-cause readmissions).

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Background: Data regarding ischemic postconditioning during percutaneous coronary intervention (PCI) as compared conventional PCI alone has yielded conflicting results.

Methods: Online databases comparing use of ischemic postconditioning percutaneous coronary intervention (ICP-PPCI) in STEMI patients with conventional PPCI were selected. Mortality, heart failure (HF), myocardial infarction (MI), and major adverse cardiac events (MACE) were evaluated.

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Introduction: The cause-and-effect relationship of QTc prolongation in Coronavirus disease 2019 (COVID-19) patients has not been studied well.

Objective: We attempt to better understand the relationship of QTc prolongation in COVID-19 patients in this study.

Methods: This is a retrospective, hospital-based, observational study.

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Background: The use of direct oral anticoagulants (DOAC) in preference to vitamin K antagonists (VKA) as a treatment of left ventricle (LV) thrombus is controversial.

Methods: Literature search for full-text articles and conference abstracts was performed using PubMed, EMBASE databases search was performed to identify articles that compared use of DOAC vs. VKA in patients with LV thrombus.

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