Publications by authors named "Sheikh Farzana Zaman"

Article Synopsis
  • - Jamaican children are exposed to mercury (Hg) primarily through their diet, particularly from consuming saltwater and canned fish, which can negatively affect neurodevelopment.
  • - The study examined the relationship between environmental Hg exposure, specific GST genes (GSTT1, GSTM1, GSTP1), and blood mercury concentrations in a sample of 375 children aged 2-8.
  • - Results showed that the impact of consuming canned fish on blood Hg levels is stronger in children with specific GSTP1 genotypes, emphasizing the need for further research in other populations.
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: To assess the safety and reactogenicity of single oral dose of heat-stable rotavirus vaccine (HSRV) in healthy adults aged 18-45 years followed by assessment of safety, reactogenicity, and immunogenicity of three doses of HSRV in healthy infants aged 6-8 weeks at enrollment.: Single-center randomized controlled, sequential, blinded (adults) and open-label (infants).: Single site at International Center for Diarrheal Disease Research, Bangladesh (icddr,b).

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Background: To support vaccination programs in developing countries, a 4-dose vial presentation of pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) was developed. This study assessed immunologic non-inferiority and safety of the investigational PHiD-CV 4-dose versus licensed 1-dose vial presentation in infants.

Methods: In this phase III, mono-center, observer-blind study in Bangladesh, 6-10-week-old infants were randomized 1:1 to receive PHiD-CV primary vaccination (at ages 6, 10, 18 weeks) and a booster dose (at age 9 months) with a 4-dose vial (with preservative, 4DV group) or 1-dose vial (preservative-free, 1DV group).

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