The role of industry 4.0 enabling technologies for predicting, and managing of algal blooms: Bridging gaps and unlocking potential.

Recent advancements in data analytics, predictive modeling, and optimization have highlighted the potential of integrating algal blooms (ABs) with Industry 4.0 technologies. Among these innovations, digital twins (DT) have gained prominence, driven by the rapid development of artificial intelligence (AI) and machine learning (ML) technologies, particularly those associated with the Internet of Things (IoT).

Takayasu Arteritis Complicated by Superior Mesenteric Artery Stenosis and Bilateral Renal Arteritis: A Clinical Case Report.

Takayasu arteritis (TA), a rare large-vessel vasculitis, primarily affects women of childbearing age, causing granulomatous inflammation in the aorta and its major branches. This inflammation can lead to stenosis, aneurysms, or occlusion, with the abdominal aorta, subclavian, and brachial arteries commonly involved. We present the case of a 26-year-old female with TA with a rare involvement of the superior mesenteric artery (SMA).

Machine learning-based monitoring and design of managed aquifer rechargers for sustainable groundwater management: scope and challenges.

Managed aquifer recharge (MAR) replenishes groundwater by artificially entering water into subsurface aquifers. This technology improves water storage, reduces over-extraction, and ensures water security in water-scarce or variable environments. MAR systems are complex, encompassing various components such as water storage, soil, meteorological factors, groundwater management (GWM), and receiving bodies.

Nanotechnology in action: silver nanoparticles for improved eco-friendly remediation.

Nanotechnology is an exciting area with great potential for use in biotechnology due to the far-reaching effects of nanoscale materials and their size-dependent characteristics. Silver and other metal nanoparticles have attracted a lot of attention lately because of the exceptional optical, electrical, and antimicrobial characteristics they possess. Silver nanoparticles (AgNPs) stand out due to their cost-effectiveness and abundant presence in the earth's crust, making them a compelling subject for further exploration.

Mental Health, Sleep Quality, and Psychological Well-Being during the Holy Month of Ramadan.

Objectives: Ramadan, a significant month for Muslims, presents unique challenges, particularly in the context of the USA. This study aimed to explore the relationship between mental health factors (depression, anxiety, and stress), sleep quality, and psychological well-being (subjective happiness and life satisfaction) during the month of Ramadan among participants and by gender.

Methods: This study enlisted 163 participants (74% female, 25.

Digitalization of phosphorous removal process in biological wastewater treatment systems: Challenges, and way forward.

Phosphorus in wastewater poses a significant environmental threat, leading to water pollution and eutrophication. However, it plays a crucial role in the water-energy-resource recovery-environment (WERE) nexus. Recovering Phosphorus from wastewater can close the phosphorus loop, supporting circular economy principles by reusing it as fertilizer or in industrial applications.

Embryonal rhabdomyosarcoma of the testis in a 17-year-old male.

Primary rhabdomyosarcoma of the testis is an exceptionally rare and highly malignant sarcoma. To date, there are only 23 reported cases in the literature. We report a 17-year-old male patient presented with massive scrotal swelling that had been progressively enlarging over seven-months.

Green approach for the fabrication of dual-functional S/N doped graphene tagged ZnO nanograins for in vitro bioimaging and water pollutant remediation.

Dual-functional S/N (sulfur and nitrogen) doped graphene-tagged zinc oxide nanograins were synthesized for bioimaging applications and light-dependent photocatalytic activity. Applying the green synthesis approach, graphene was synthesized from kimchi cabbage through a hydrothermal process followed by tagging it with synthesized zinc oxide nanoparticles (ZnO-NPs). The 2D/0D heterostructure prepared by combining both exhibited exceptional advantages.

Therapeutic targeting of the tumor microenvironments with cannabinoids and their analogs: Update on clinical trials.

Cancer is a major global public health concern that affects both industrialized and developing nations. Current cancer chemotherapeutic options are limited by side effects, but plant-derived alternatives and their derivatives offer the possibilities of enhanced treatment response and reduced side effects. A plethora of recently published articles have focused on treatments based on cannabinoids and cannabinoid analogs and reported that they positively affect healthy cell growth and reverse cancer-related abnormalities by targeting aberrant tumor microenvironments (TMEs), lowering tumorigenesis, preventing metastasis, and/or boosting the effectiveness of chemotherapy and radiotherapy.

Antioxidant and antiproliferative activity of against colorectal cancer.

, a green leafy vegetable with remarkable nutraceutical potential is widely used since ancient times to maintain a healthy colon. This plant has been investigated for its medicinal potential due to the increase in young adult cases of colorectal cancer each year. This study was accomplished to investigate methanolic extract (BaME) antioxidant and anticancer properties.

Fractional-order models identification and control within a supervisory control framework for efficient nutrients removal in biological wastewater treatment plants.

Wastewater treatment plants (WWTPs) are highly non-linear processes that must be optimized to meet rigorous environmental water regulations. In this context, efficiency and costs are equally important terms. The ASM3bioP framework is employed in this study to enable simultaneous nitrogen and phosphorus removal using an activated sludge process model with seven-reactor configurations.

Fractional order-based hierarchical controller design and evaluation with Bürger-Diehl settler model in a total nitrogen removal wastewater treatment process.

The primary objective of this study was to establish two-level structured control techniques based on the globally known benchmark simulation model no. 1 (BSM1) and the Bürger-Diehl settler model in order to improve effluent quality. The latter was based on the activated sludge model no.

Integrated supervisory and override control strategies for effective biological phosphorus removal and reduced operational costs in wastewater treatment processes.

A novel control strategy is developed for a municipal wastewater treatment plant (WWTP) consisting of anaerobic-anoxic-aerobic reactors. The idea is to generate more organic matter with a reduction of nitrate concentration in the anoxic section so that more biological phosphorus (P) removal happens. For this, the Supervisory and Override Control Approach (SOPCA) is designed based on the benchmark simulation model (BSM1-P) and is evaluated by considering dynamic influent.

The anti-cancerous activity of adaptogenic herb Astragalus membranaceus.

Background: Cancer is the most dreadful disease increasing rapidly causing an economic burden globally. A standardized chemotherapy regimen planned with curative intent weakens the immune system and damages healthy cells making the patient prone to infections and severe side effects with pain and fatigue.

Purpose: Astragalus membranaceus (AM) has a long history of use in the treatment of severe adverse diseases.

Effect of Multimorbidity on Fragility Fractures in Community-Dwelling Older Adults: Shimane CoHRE Study.

Fragility fractures (FFxs), which are a common musculoskeletal injury in older adults, is associated with an increased frequency of falls. Both FFxs and falls may result from drugs, habits, and co-occurring diseases. We aimed to evaluate the effects of various diseases on the risk of FFx.

Targeting key transcriptional factor STAT3 in colorectal cancer.

In developed countries, colorectal cancer (CRC) is the fourth most common cancer and the second leading cause of malignant-related deaths. CRC is treatable cancer when diagnosed early; however, diagnosis at the advanced stage is associated with a poor prognosis. Although chemotherapy is generally very promising, STAT3 protein which is overexpressed and persistently activated in CRC cells is observed to be the major contributor of chemoresistance development.

Supervisory control configurations design for nitrogen and phosphorus removal in wastewater treatment plants.

Model predictive control (MPC) and Fuzzy controllers are designed in a two-level hierarchical supervisory control framework for control of activated sludge-based wastewater treatment plants (WWTP) in order to efficiently remove nitrogen and phosphorus. Benchmark simulation model No.3 with a bio-phosphorus (ASM3bioP) module is used as a working platform.

Integration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance.

The development of reliable, mixed-culture biotechnological processes hinges on understanding how microbial ecosystems respond to disturbances. Here we reveal extensive phenotypic plasticity and niche complementarity in oleaginous microbial populations from a biological wastewater treatment plant. We perform meta-omics analyses (metagenomics, metatranscriptomics, metaproteomics and metabolomics) on in situ samples over 14 months at weekly intervals.

A systematic analysis of the optimization of computerized physician order entry and clinical decision support systems: A qualitative study in English hospitals.

This article analyzes the range of system optimization activities taking place over an extended period following the implementation of computerized physician order entry and clinical decision support systems. We undertook 207 qualitative semi-structured interviews, 24 rounds of non-participant observations of meetings and system use, and collected 17 organizational documents in five hospitals over three time periods between 2011 and 2016. We developed a systematic analysis of system optimization activities with eight sub-categories grouped into three main categories.

Hibernoma: A missed diagnosis!!

Hibernoma is a rare, benign soft tissue tumor described in <200 case reports/case series. It is slow-growing, painless, and commonly mistaken for lipoma or liposarcoma. Histopathological diagnosis is must for confirmation.

Citizens' Access to Their Digital Health Data in Eleven Countries - A Comparative Study.

Governments around the world are actively promoting citizens electronic access to their health data as one of a number of ways to respond to the challenges of health care delivery in the 21st century. While numerous approaches have been utilized it is evident from cross-country comparisons that there are different conceptualizations of: both the expected and desired roles for citizens in the management of their own health; the benefits that will be delivered by citizen access and how these benefits should be measured and benchmarked over-time. This paper presents comparative analyses of the methods by which citizens are provided with access to their own health data across 11 countries.

In situ phenotypic heterogeneity among single cells of the filamentous bacterium Candidatus Microthrix parvicella.

Microorganisms in biological wastewater treatment plants require adaptive strategies to deal with rapidly fluctuating environmental conditions. At the population level, the filamentous bacterium Candidatus Microthrix parvicella (Ca. M.

Integrated omics for the identification of key functionalities in biological wastewater treatment microbial communities.

Biological wastewater treatment plants harbour diverse and complex microbial communities which prominently serve as models for microbial ecology and mixed culture biotechnological processes. Integrated omic analyses (combined metagenomics, metatranscriptomics, metaproteomics and metabolomics) are currently gaining momentum towards providing enhanced understanding of community structure, function and dynamics in situ as well as offering the potential to discover novel biological functionalities within the framework of Eco-Systems Biology. The integration of information from genome to metabolome allows the establishment of associations between genetic potential and final phenotype, a feature not realizable by only considering single 'omes'.