Publications by authors named "Sheida Zoughi"

Article Synopsis
  • Cancer is a major non-communicable disease that requires early diagnosis through the identification of specific biomarkers, with microRNAs (miRNAs) emerging as promising options; miR-21, in particular, is known to be overexpressed in various cancers.
  • A novel biosensor using silver nanoclusters (AgNCs) was developed to detect miR-21, employing a specialized hairpin sequence and a guanine-rich sequence to enhance fluorescence signals, which increased in the presence of miR-21.
  • The biosensor demonstrated effective detection of miR-21 in a linear range of concentrations and was successfully tested on human plasma and cancer cell samples, offering a simpler, cost-effective method for miRNA detection without
View Article and Find Full Text PDF
Article Synopsis
  • Early fetal sex determination is essential for managing prenatal diagnoses of X-linked genetic issues and congenital adrenal hyperplasia.
  • The study created a new, efficient method using DNA biosensors based on carbon nanotubes to detect fetal DNA in maternal blood samples.
  • The biosensors showed significant fluorescence recovery when target DNA was present, demonstrating their potential for accurate and early fetal sex detection with specific limits of detection for each probe used.
View Article and Find Full Text PDF

In this study, a citalopram optical nano-sensor was developed. Citalopram is a well-known antidepressant drug that reduces the reuptake of serotonin in neurons as a result, serotonin neurotransmission, the primary response to antidepressant treatments, increases in many parts of the brain. This study introduces a carbon quantum dots (CQDs)-based optical nanosensor for rapid detection of citalopram.

View Article and Find Full Text PDF

A fluorescent assay for the selective analysis of tartrazine was developed. Tartrazine is a health-threatening food additive commonly used as fake saffron. An optical nanosensor was fabricated based on molecular imprinting technique in which carbon dots (CDs) as fluorophores and tartrazine as a template molecule were embedded in molecularly imprinted polymer (MIP) matrix.

View Article and Find Full Text PDF