Oesophageal stricturing secondary to adult Stevens-Johnson syndrome: similarities in presentation and management to corrosive injury.

Clinical decisions often have to be made in the absence of evidence. In some cases, it is appropriate to use evidence from similar but more common conditions for which studies have resulted in evidence-based practice. This report describes a case of oesophageal stricture following Stevens-Johnson syndrome illustrating this concept, although it is likely that there are many other conditions in which the same principle will stand the clinician in good stead.

Predictable and unpredictable hazards of erythropoietic protoporphyria.

A female patient with a long history of erythropoietic protoporphyria developed progressive rapid derangement of hepatic function requiring urgent orthotopic liver transplantation. In the immediate post-operative period the patient developed unusual and serious complications, including a generalized axonal neuropathy, intestinal ulceration and a large second-degree phototoxic burn of the abdominal wall. Recovery was achieved only after prolonged intensive hospital care and rehabilitation.

Epidemiological survey of standard series patch test results and observations on day 2 and day 4 readings.

Computer data on 4721 consecutive patients patch tested with an extended standard series were analysed for the frequency of allergic reactions to each substance. Particular attention was given to the negative first reading at day 2 (D2) which later became positive at day 4 (D4). A total of 4210 allergic reactions were recorded.

Photodermatitis due to spot welding.

The case of a patient with a 1-year history of recurrent, severe facial dermatitis is reported. The role of ultraviolet radiation from arc welding or other equipment at work in inducing dermatitis is discussed.

Granulomatous cheilitis and a positive Kveim test.

A female patient with a protracted history of multitudinary symptoms more recently developed granulomatous cheilitis (GC) and underwent extensive investigations. Her Kveim test was positive.