Paternal impact on the developmental programming of sexual dimorphism.

Sexual dimorphism involves distinct anatomical, physiological, behavioral, and developmental differences between males and females of the same species, influenced by factors prior to conception and during early development. These sex-specific traits contribute to varied phenotypes and individual disease risks within and across generations and understanding them is essential in mammalian studies. Hormones, sex chromosomes, and imprinted genes drive this dimorphism, with over half of quantitative traits in wildtype mice showing sex-based variation.

Effect of Smoking on Seminal Plasma Vitamin B in Fertile and Subfertile Men.

Despite extensive documentation of the negative consequences of smoking on a wide range of diseases and disorders, the direct effect of smoking on seminal plasma vitamin B (vitB) concentration is not addressed yet. Here, we attempted to examine the influence of smoking on the levels of seminal plasma vitB in fertile and subfertile males. One hundred and ninety-five participants were categorized into two groups: fertile men (smokers ( = 32), nonsmokers ( = 43)) and subfertile men (smokers ( = 65), nonsmokers ( = 55)).

Role of pyridoxine and oxidative stress in asthenozoospermia.

Purpose: Infertility is a worldwide concern, and recent research indicates that vitamin B deficiency may play a role in male infertility, primarily by inducing hyperhomocysteinemia and oxidative stress. These processes can have a detrimental effect on semen quality, ultimately affecting male fertility. Here, we aim to evaluate the biochemical status of pyridoxine (vitamin B) in relation to total glutathione and total antioxidant capacity.

Men with oligozoospermia had lower level of seminal plasma pyridoxine compared to normozoospermic men.

The contribution of pyridoxine on various human disorders has been revealed in so many studies; however, this contribution on poor semen quality has yet to be investigated. Here, we intended to measure the level of seminal plasma pyridoxine (SPP) in men with oligozoospermia compared to normozoospermic men. Thirty-three men with oligozoospermia and forty-three normozoospermic men were randomly enrolled in this study.

Seminal plasma vitamin B levels in men with asthenozoospermia and men with normal sperm motility, a measurement using liquid chromatography with tandem mass spectrometry.

There is growing evidence that vitamin B has a valuable contribution in maintaining normal sperm parameters; however, this contribution has not yet well-identified. Here, we aimed to measure the level of seminal plasma vitamin B in men with asthenozoospermia compared to men with normal sperm motility. Ninety-seven human males with asthenozoospermia and eighty-eight human males with normal sperm motility (control) were recruited in this study.