Synopsis of recent research by authors named "Sheetal Sinha"
- Sheetal Sinha's research primarily focuses on antimicrobial peptides (AMPs) and their potential as novel treatments for multi-drug-resistant Gram-negative bacterial infections, particularly emphasizing the role of the peptide Thanatin in overcoming the challenges posed by the outer membrane lipopolysaccharide (LPS).
- Recent studies highlight Thanatin's dual mode of action, its structural properties, and its interactions with microbial membranes, providing insights into its mechanism as a potent antimicrobial agent with low hemolytic toxicity, applicable for antibiotic development.
- Sinha's work also explores intelligent drug delivery systems and the pharmacodynamics of synthetic peptides, contributing to the broader understanding of antimicrobial strategies to address the urgent need for new treatments against resistant pathogens.
