Publications by authors named "Sheen-Woo Lee"

Article Synopsis
  • The study aimed to compare the image quality and diagnostic performance between low-dose CT urography and conventional CT performed through a dual-source CT system.
  • The research found that low-dose CT had noticeably higher noise levels, resulting in poorer image quality as assessed by two radiologists, but diagnostic capabilities were similar for identifying urinary tract diseases.
  • Ultimately, low-dose CT, which used only 25% of the typical radiation dose, proved to be just as effective as conventional CT for diagnosing urinary conditions despite its lower image quality.
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  • - The study aimed to compare two MRI techniques (BLADE DWI and RESOLVE DWI) for detecting metastatic lesions in the pelvic bones, analyzing the relationship between their imaging parameters and FDG uptake in PET/CT scans.
  • - It involved 58 bone lesions from 19 patients and revealed that ADC values from both MRI methods were significantly higher in metastatic lesions compared to benign red marrow hyperplasia, with BLADE providing better image quality and higher SNR despite longer imaging times.
  • - Statistical analyses showed a poor correlation between the imaging parameters (ADC and SUV values), indicating that these metrics may not reliably predict each other in the context of distinguishing metastatic from benign lesions.
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  • The study investigates how thigh fat and muscle characteristics, as seen on CT scans, affect cardiovascular outcomes in elderly patients who have suffered hip fractures.
  • Researchers analyzed data from 356 patients aged 65 and older, focusing on computed tomography-derived features like cross-sectional area and compactness of thigh fat and muscle.
  • Results indicated that patients who experienced major adverse cardiovascular events (MACE) had significantly lower thigh fat area and fat compactness compared to those who did not, suggesting a possible link between thigh fat characteristics and cardiovascular risk.
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  • The study aimed to analyze T1 and T2 relaxation times of bone marrow lesions in the spine and pelvis using magnetic resonance fingerprinting (MRF), focusing on differences between bone metastases, red marrow, and fatty marrow.
  • Sixty patients were assessed, with two radiologists measuring the T1 and T2 values of metastatic bone lesions and different types of marrow, finding a significant difference in T1 values for osteoblastic metastases compared to red marrow, while T2 values showed no significant differences.
  • The research highlights the effectiveness of MRF in quantifying bone marrow characteristics, indicating that T1 values could be particularly beneficial in differentiating between types of bone lesions with high inter-ob
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Musculoskeletal pain is a significant contributor to disability. The mechanism and target of the treatment should be optimized by imaging, but currently no accepted gold standard exists to image pain. In addition to end-organ pathology, other mediators also contribute to nociception, such as angiogenesis, axonal extension, immunologic modulation, and central sensitization.

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We present a rare case of myoepithelioma in the subcutaneous layer of the shoulder with ultrasonography (US) and magnetic resonance imaging (MRI). US showed a lobulated hyperechoic mass, leading to an impression of lipoma. MRI showed the mass with low signal intensity on T1-weighted images (T1WI), high signal intensity on fat-suppressed T2-weighted images (T2WI), intermediate signal intensity on T2WI, and intense enhancement with adjacent fascial thickening.

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Introduction: Adequate bone quality is essential for long term biologic fixation of cementless total knee arthroplasty (TKA). Recently, vertebral bone quality evaluation using dual-energy computed tomography (DECT) has been introduced. However, the DECT bone mineral density (BMD) in peripheral skeleton has not been correlated with Hounsfield units (HU) or central dual-energy X-ray absorptiometry (DXA), and the accuracy remains unclear.

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Objectives: This research aims to apply an auditory display for tumor imaging using fluorescence data, discuss its feasibility for in vivo tumor evaluation, and check its potential for assisting enhanced cancer perception. Methods: Xenografted mice underwent fluorescence imaging after an injection of cy5.5-glucose.

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Purpose: The diagnostic tool for Kümmell's disease (KD), including the intravertebral vacuum cavity on imaging, is still limited. The purpose of this study was to find other magnetic resonance imaging (MRI) findings that could help the diagnosis of KD.

Methods: A total of 289 patients (103 males and 186 females with a mean age of 69 ± 15 years) with thoracolumbar compression fracture were included.

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Purpose: We aimed to analyze the prevalence, causes, and clinical settings of 4-year critical radiologic reports (CRRs) notified from the musculoskeletal section of the radiology department. Then, we investigated the communication outcomes.

Methods: This study was approved by our institutional review board.

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Purpose: To investigate the feasibility of using 3-dimensional MRF for bone marrow evaluation in the field of view of prostate MRI for T1 and T2 quantification of prostate cancer bone metastases, as well as comparing it to the ADC value.

Methods: In this retrospective study, 30 prostate MRIs were included: 14 cases with prostate cancer bone metastasis and 16 cases without prostate cancer (control). MRF was obtained twice before (nonenhanced [NE] MRF) and after contrast injection (contrast-enhanced [CE] MRF), and T1 and T2 maps were generated from each MRF.

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Purpose: This study aimed to stratify risk factors and vein levels for postoperative deep vein thrombosis (DVT) after lower-extremity orthopedic surgery.

Methods: Ninety-nine patients who underwent Doppler ultrasonography after lower-extremity orthopedic surgery were enrolled. Medical records were reviewed for anesthesia duration, type of surgery, body weight, height, and cardiovascular risk factors (including history of smoking, diabetes mellitus or hypertension, blood pressure, and total cholesterol and high-density lipoprotein [HDL] cholesterol levels), and the DVT treatment.

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Purpose: To evaluated the added value of dual-energy CT (DECT) virtual non-calcium (VNCa) protocol on conventional CT in the detection of acute knee fractures in non-radiology inexpert readers.

Method: One hundred fifty-six patients (mean age, 51.97 years; age range, 17-86 years) with knee trauma, who underwent DECT and MRI within 3 days between April 2017 and October 2018, were retrospectively analyzed.

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Objective: The purpose of this article is to assess whether dual-energy CT (DECT) collagen material decomposition technique could reliably depict graft integrity in patients with knee ligament reconstruction.

Methods: Seventy patients (mean age, 29.8 years; age range, 15-57 years; 61 men, 9 women) who underwent knee DECT, from June 2016 to January 2018, after knee ligament reconstruction were included in our study.

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Objective: The clinical application of endoscopic techniques for lumbar lateral recess stenosis (LRS) is still challenging. This study aimed to describe a transforaminal endoscopic decompression (TED) technique for LRS and to demonstrate its clinical results.

Methods: Two-year follow-up data were collected from 45 consecutive patients who underwent TED for LRS.

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Background: The ability to accurately diagnose and objectively localize pain generators in chronic pain sufferers remains a major clinical challenge since assessment relies on subjective patient complaints and relatively non-specific diagnostic tools. Developments in clinical molecular imaging, including advances in imaging technology and radiotracer design, have afforded the opportunity to identify tissues involved in pain generation based on their pro-nociceptive condition. The sigma-1 receptor (S1R) is a pro-nociceptive receptor upregulated in painful, inflamed tissues, and it can be imaged using the highly specific radioligand F-FTC-146 with PET.

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Objectives: In dual-source CT, dual-energy (DE) performance is affected by various X-ray tube voltage combinations with and without tin filter (Sn). The purpose of this study was to assess the utility of the 80/150 Sn kV voltage combination in terms of image artefact and radiation dose for DECT gout protocol, compared with the conventional 80/140 kV.

Methods: Seventy-four patients with suspected gout who underwent dual-source DECT examinations scanned at 80/140 kV (n = 37) and at 80/150 Sn kV (n = 37) were included.

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Background: Lumbosacral transitional vertebrae (LSTV) are a relatively common variant and have been considered as one of the reasons for back pain. It is not unusual for clinicians to encounter patients with LSTV who require caudal epidural block (CEB) for pain management.

Objective: We investigated the termination level of the dural sac (DS) and anatomical features of the lumbosacral region relevant to CEB in patients with LSTV and compared these findings between sacralization and lumbarization groups.

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We report the sonographic appearance of a rare case of neuritis ossificans of the median nerve at the wrist, which appeared as a hyperechoic lesion around the nerve. Diagnosis was confirmed with magnetic resonance imaging (MRI).

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Rationale: Although antipsychotic treatment often causes weight gain and lipid abnormalities, quantitative analyses of tissue-specific body fat content and its distribution along with adipokines have not been reported for antipsychotic-treated patients.

Objectives: The purposes of the present study were to quantitatively assess abdominal and liver fat in patients with schizophrenia on antipsychotic treatment and age- and body mass index (BMI)-matched healthy controls and to evaluate their associations with plasma leptin and adiponectin levels.

Methods: In 13 schizophrenia patients on antipsychotic treatment and 11 age- and BMI-matched controls, we simultaneously quantified visceral and subcutaneous fat content using T1-weighted magnetic resonance imaging and liver fat content by H magnetic resonance spectroscopy.

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Article Synopsis
  • Reliable MRI diagnoses are crucial for identifying posterolateral corner (PLC) injuries, especially when physical exams are limited due to multiple ligament issues.
  • The study evaluated the appearance of PLC components using both 3D isotropic MR images and traditional 2D MRI in 25 patients with confirmed PLC instability compared to 25 controls.
  • Results showed that 3D MRI was more effective in detecting ligament thickening and specific signs of injury, confirming its validity for assessing PLC abnormalities.
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  • - This study investigates how adipose tissue-derived cells (ADCs) affect fracture healing by using advanced imaging techniques on mice with femur defects.
  • - Researchers transplanted luciferase-expressing ADCs into one femur and a control substance in the other, monitoring changes over 20 days via micro-CT and bioluminescence imaging.
  • - Findings indicate that ADCs promote increased bone density around the implant site, suggesting they play a positive role in the fracture healing process despite limited cell migration.
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Objective: To estimate and compare radiation exposure during transforaminal fluoroscopy-guided epidural steroid injection (TFESI) at different vertebral levels.

Materials And Methods: Fluoroscopy-guided TFESI was performed in 181 patients. The patients were categorized into three groups according to the injected lumbosacral nerve level of L2-4, L5, or S1.

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There are conflicting data describing the effect of mesenchymal stem cells (MSCs) on tumorigenesis. The present study aimed to determine the survival rate and effect of adipose tissue-derived MSCs (ADMSCs) in tumor growth using bioluminescence imaging (BLI) and ultrasound (US) in an osteosarcoma xenograft model. Firefly luciferase-expressing ADMSCs combined with the osteosarcoma cell line UMR-106 in 4 different proportions (5, 10, 15 and 25%, named G1-G4, respectively) were xenografted into the right flanks of nude mice.

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