Publications by authors named "SheLan Liu"

What Is Already Known About This Topic?: Human respiratory syncytial virus (HRSV) coinfection with other respiratory pathogens frequently occurs in young children with acute respiratory illness. However, the epidemiological patterns and associated disease burden of HRSV coinfections in pediatric populations remain poorly characterized.

What Is Added By This Report?: Analysis of hospitalized children under 5 years in Zhejiang Province from 2018 to 2023 revealed that 20.

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Article Synopsis
  • In a study analyzing over 28,000 scarlet fever cases in Zhejiang Province, China, researchers found a significant decrease in incidence during the COVID-19 pandemic, particularly in 2020.
  • The sharpest decline was among young children (ages 0-4), where cases dropped by 67.3%.
  • The findings indicate that the pandemic altered not only the incidence but also the seasonal pattern of scarlet fever, suggesting implications for future prevention and control strategies.
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The COVID-19 pandemic overwhelmed national health care systems, not least in the context of hepatitis elimination. This study investigates the effects of the pandemic response on the incidence rate, mortality rate, and case fatality rate (CFR) for hepatitis C virus (HCV) cases in China. We extracted the number of hepatitis C cases and HCV-related deaths by month and year for 2015 to 2021 in China and applied two proportional tests to analyze changes in the average yearly incidence rates, mortality rates, and CFRs for 2015 to 2020.

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Background: In May-June 2023, an unprecedented outbreak of human respiratory syncytial virus (HRSV) infections occurred in a kindergarten, Zhejiang Province, China. National, provincial, and local public health officials investigated the cause of the outbreak and instituted actions to control its spread.

Methods: We interviewed patients with the respiratory symptoms by questionnaire.

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Introduction: The COVID-19 pandemic continues to ravage the world, and mutations of the SARS-CoV-2 continues. The new strain has become more transmissible. The role of aerosol transmission in the pandemic deserves great attention.

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is the pathogen of psittacosis and infects a wide range of birds and even humans. Human infection occurs most commonly in those with a history of contact with birds or poultry. We describe a case of psittacosis in a human immunodeficiency virus infected patient in Zhejiang Province for the first time.

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  • The study analyzes trends in acute hepatitis of unspecified aetiology (HUA) in China from 2004 to 2021, revealing a significant decrease in both incidence and mortality rates.
  • A total of 707,559 HUA cases were reported over the years, with the proportion of HUA in viral hepatitis dropping from 7.55% in 2004 to 0.72% by 2021.
  • Despite the decline, the need for continued monitoring and improvements in public health policies regarding HUA remains critical in China.
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Objectives: The aim of this study is to describe, visualize, and compare the trends and epidemiological features of the mortality rates of 10 notifiable respiratory infectious diseases in China from 2004 to 2020.

Setting: Data were obtained from the database of the National Infectious Disease Surveillance System (NIDSS) and reports released by the National and local Health Commissions from 2004 to 2020. Spearman correlations and Joinpoint regression models were used to quantify the temporal trends of RIDs by calculating annual percentage changes (APCs) in the rates of mortality.

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Background: In response to the coronavirus disease 2019 (COVID-19) pandemic, the Chinese government implemented the dynamic COVID-zero strategy. We hypothesized that pandemic mitigation measures might have reduced the incidence, mortality rates, and case fatality ratios (CFRs) of the human immunodeficiency virus (HIV) in 2020-2022.

Method: We collected HIV incidence and mortality data from the website of the National Health Commission of the People's Republic of China from January 2015 to December 2022.

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  • The study compares fatal cases of COVID-19 and H7N9 in mainland China, focusing on clinical features and survival factors.
  • It found similar demographic characteristics but differences in treatment effectiveness; H7N9 patients received more aggressive treatment than COVID-19 patients.
  • Key protective factors for survival in COVID-19 included antibiotics, oxygen treatment, and corticosteroids, while antiviral drugs and corticosteroids were beneficial for H7N9 fatal cases, highlighting the need for ongoing pandemic surveillance.
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The gut microbiota affects many aspects of host biology and plays key roles in the coevolutionary association with its host. Geographical gradients may play a certain role on gut microbiota variation in the natural environment. However, the distribution pattern of amphibian gut microbiota in the latitudinal gradient remains largely unexplored.

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Objective: Human adenovirus (HAdV) coinfection with other respiratory viruses is common, but adenovirus infection combined with human coronavirus-229E (HCoV-229E) is very rare.

Study Design And Setting: Clinical manifestations, laboratory examinations, and disease severity were compared between three groups: one coinfected with HAdV-Ad7 and HCoV-229E, one infected only with adenovirus (mono-adenovirus), and one infected only with HCoV-229E (mono-HCoV-229E).

Results: From July to August 2019, there were 24 hospitalized children: two were coinfected with HAdV-Ad7 and HCoV-229E, and 21 were infected with a single adenovirus infection.

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A cluster of Chlamydia psittaci (C. psittaci) cases was reported in Zhejiang Province, China, 2019. This study evaluates the extent of the outbreak and determines the source of infection.

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Background: The increasing of exchange activities among public health institutes and experts globally calls for a standardized operation to construct public health field investigation and short-term study hub (Field Study Hub). This can funcion as a platform to share experience in public health development in an accurate and comprehensive manner that would benefit global practices. This research aims to establish a supportive indicator system to guide the construction work.

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In 2019, an outbreak of pharyngoconjunctival fever (PCF) occurred at a swimming center in Zhejiang Province, China. A total of 97 (13.55%) of the 716 amateur swimmers had illnesses, with 24 patients (24.

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The incidence of scarlet fever and pertussis has increased significantly in China in recent years. During the COVID-19 pandemic, stringent non-pharmaceutical intervention measures were widely adopted to contain the spread of the virus, which may also have essential collateral impacts on other infectious diseases, such as scarlet fever and pertussis. We compared the incidence data of scarlet fever and pertussis in Mainland China and Hong Kong from 2004 to 2021 before and after the COVID-19 pandemic.

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Currently, people all over the world have been affected by coronavirus disease 2019 (COVID-19). Fighting against COVID-19 is the top priority for all the countries and nations. The development of a safe and effective COVID-19 vaccine is considered the optimal way of ending the pandemic.

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Article Synopsis
  • The report discusses a rare tumor in the retina called a vasoproliferative tumor (VPTR) along with a serious case of secondary epiretinal membrane (ERM) in a 56-year-old male patient.
  • The patient received two rounds of laser photocoagulation (LP) to treat the tumor, with complications such as worsening of the ERM observed after the first treatment.
  • After the second LP treatment, the ERM showed improvement within five months, suggesting that LP could be a useful treatment option for cases of VPTR with severe ERM.
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Background: This study explored the effect of a continuous mitigation and containment strategy for coronavirus disease 2019 (COVID-19) on five vector-borne diseases (VBDs) in China from 2020 to 2021.

Methods: Data on VBDs from 2015 to 2021 were obtained from the National Health Commission of the People's Republic of China, and the actual trend in disease activity in 2020-2021 was compared with that in 2015-2019 using a two-ratio Z-test and two proportional tests. Similarly, the estimated trend in disease activity was compared with the actual trend in disease activity in 2020.

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Potential zoonotic pathogens may be transmitted from wildlife to humans through the illegal wild meat trade, which has become a pressing issue. However, research on the antimicrobial resistance genes (ARGs) of Malayan pangolin (Manis javanica) intestinal bacteria is limited. Here, multidrug-resistant Escherichia coli M172-1 (ST354) isolated from Malayan pangolin feces in 2019 was found to be resistant to 13 antibiotics.

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The Yangtze River Delta is one of the top five Chinese regions affected by COVID-19, as it is adjacent to Hubei Province, where COVID-19 first emerged. We investigated the impact of COVID-19 non-pharmaceutical interventions (NPIs) on changes in respiratory infectious diseases (RIDs) incidence and air quality in the Yangtze River Delta by constructing two proportional tests and fitting ARIMA and linear regression models. Compared with the pre-COVID-19 period, the average monthly incidence of seven RIDs decreased by 37.

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The public health interventions to mitigate coronavirus disease 2019 (COVID-19) could also potentially reduce the global activity of influenza. However, this strategy's impact on other common infectious diseases is unknown. We collected data of 10 respiratory infectious (RI) diseases, influenza-like illnesses (ILIs), and seven gastrointestinal infectious (GI) diseases during 2015-2020 in China and applied two proportional tests to check the differences in the yearly incidence and mortality, and case-fatality rates (CFRs) over the years 2015-2020.

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Outbreaks of acute hemorrhagic conjunctivitis (AHC) are associated with a high disease burden. In this study, we investigated the association between enhanced public health intervention and the incidence of AHC during the COVID-19 pandemic in China. A total of 212,526 AHC cases were reported in China during 2015-2020.

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