[Study of the prevalence of antibodies to some arboviruses in the population of the Republic of Guinea].

Introduction: Acute febrile diseases kill more than 250,000 people annually in West Africa. Malaria and typhoid fever traditionally occupy most of the total structure of registered fevers. However, these data do not fully reflect the true overall disease patterns in the West African region.

[Fungal keratitis after penetrating keratoplasty].

The article presents a case of fungal keratitis after penetrating keratoplasty (PKP). A 35-years old patient had previously undergone surgical removal of an intraocular foreign body and developed chronic keratouveitis and epithelial-endothelial corneal dystrophy. PKP and early postoperative period were uneventful.

A STUDY OF THE ULTRASTRUCTURE OF THE SURFACE OF THE TRANSPLANTABLE LINE VERO CELLS INFECTED WITH THE RABIES VIRUS (RABV, LISSAVIRUS, RHABDOVIRIDAE).

Characteristics of the effect of attenuated rabies virus strain «Moscow 3253» on morphological parameters of transplantable line Vero cells were studied by atomic force microscopy (AFM). Methods based on phase contrast microscopy and immunofluorescence were used to confirm the specificity of interaction and to identify the infectious activity of the rabies virus. Images of intact Vero cells and Vero cells infected with rabies virus were obtained at different periods of cultivation.

WEST NILE FEVER IN THE SARATOV REGION IN 2013-2015.

West Nile virus (WNV) circulation in the territory of Saratov region and its role in the infectious pathology were investigated. For this purpose, in studies conducted in 2013-2015, suspensions of bloodsucking arthropods, organs of birds and small mammals were analyzed for the presence of WNV markers (antigens and/or RNA). The seroprevalence level in live-stock animals and population of the region was evaluated; clinical samples from patients with symptoms compatible with West Nile fever (WNF) were analyzed.

Transplacental transmission of torque teno virus.

Background: TTV has been detected in almost every human tissue type or body fluid reaching near 100% prevalence. Several studies report mother-to-child postnatal transmission of TTV in infancy but the risk of transplacental transmission of TTV is still unclear.

Methods: The blood and plasma collected postpartum from 100 mother-child pairs were analyzed using TTV-specific qPCR.

[Formation of focus of West Nile fever on the territory of Saratov Region].

Aim: Detection of circulation of West Nile virus (WNV) on the territory of Saratov Region and prerequisites for formation of natural focus of West Nile fever (WNF), determination of the role of WNV in infectious pathology on the territory of the region.

Materials And Methods: of organs of small mammals, birds, blood-sucking arthropods for the presence of WNV markers (antigens and/or RNA) were studied. Clinical material from patients with symptoms not excluding WNF was studied.

[Detection of arbovirus antigens in the mosquitoes and ticks inhabiting the Saratov Region].

The paper gives the results of a study dealing with the detection of the antigens of arboviruses of West Nile, Sindbis, Batai, Crimean-Congo hemorrhagic fever, a serocomplex of Californian encephalitis in the field material gathered in the Saratov Region in 2000-2006. The bloodsucking arthropods inhabiting the region were shown to be actively involved in the circulation of arboviruses in natural biotopes. The conclusion that it is expedient to organize an annual monitoring of arbovirus-induced infections in the areas where positive findings have been notified is justified.

[ELISA and PCR test systems used to detect Crimean-Congo hemorrhagic fever virus].

Studying the sensitivity and specificity of enzyme-linked immunosorbent assay (ELISA) for the indication of Crimean-Congo hemorrhagic fever (CCHF) virus antigens and those of reverse transcription and polymerase chain reaction (RT-PCR) for the detection of CCHF virus RNA, and those of a intercerebral infection method in newborn albino mice systems for the determination of viral infectious activity established that the sensitivity of ELISA was 1-2 orders of magnitude less than that of RP-PCR. The latter proved to be better in studying the sera sampled from patients with CCHF. The results of studying the samples of H.

[The ecology and prevalence of arboviruses on the territory of the Saratov Region].

The territorial spread of Tahyna, Batai, Sindbis, West Nile fever and Crimean-Congo hemorrhagic fever viruses throughout the Saratov region in 1998 - 2000 was analyzed. The characteristics of the epizootic activity of the natural foci of these arboviruses in different landscape zones (temperate forest-steppes, steppes and semi-deserts) were calculated. The species composition of small mammals, the natural reservoirs of the causative agents of arbovirus infections, was determined.

[The effect of diet with the sour-milk product enriched with amaranth on parameters of antioxigen protection at patients with a cardiovascular pathology].

Investigation of influence of an antisclerotic diet with a probiotical sour-milk product enriched with an extract of leaves of an amaranth in patients with ishemic heart disease and hypertension was conducted. As a result of a diet were positive dynamic of clinic manifestation, lipid spectrum of blood, coagulogramms and antioxigen status.

[The study of immune structure of Astrakhan region population to West Nile virus in 1998 and 1999].

Immunostructure of the Astrakhan Region population to West Nile fever (WNF) was studied in the preepidemic period (1998) and after the outbreak (1999). Among the sera obtained in 1998, 63 (26.3%) were positive in neutralization reaction, 84 (27.

[Anti-arbovirus antibodies positive serum screening in population of Saratov].

Seroepidemiological studies revealed the existence of a population stratum immune to West Nile and Sindbis viruses in the Saratov region. Screening of 218 sera showed that the stratum immune to arboviruses increased from 1998 to 2000. The incidence of antibodies to Batai and Sindbis viruses was the highest.

[A circulation study of California serogroup and Batai viruses (fam. Bunyaviridae, genus Bunyavirus) on the territory of Saratov Province].

Examining 337 sera from Saratov healthy residents in the neutralization test with Tyaginya and Inco viruses has revealed 56 positive results (16.6%), of which 19 (5.6%) reacted only with Tyaginya virus, 13 (3.