Prevalence and intensity of schistosomiasis haematobium among school children in respect of family social conditions in a village in Dakahlia Governorate, Egypt.

A probability sample (n = 2000) of primary and preparatory school children (6-15 years old) in a rural area, in the eastern part of Nile Delta, Egypt, were examined for S. haematobium eggs using the sedimentation technique. A sub-sample, consisting of all children whose urine samples were positive, was subjected to short interview and urine examination for egg counting using the modern monofilament polyamide (Nytrel) filters.

Epidemiological, clinical and laboratory studies on parasitic infections as a cause of fever of undetermined origin in Dakahlia Governorate, Egypt.

Forty-three patients who fulfilled the international criteria for prolonged fever were exposed to thorough history taking, clinical and laboratory investigations. The latter included urine and stool examination, urine and blood culture, haemogram, liver and renal function tests, chest X-ray, tuberculin test, bone marrow, liver biopsy, blood films, serological tests including ELISA, IHA and IFA for detection of schistosomiasis, toxoplasmosis and malaria. Parasitic infections were detected in 30/43 (69.

Antibodies against toxoplasma in children and adults with malignancy.

Twenty five children and adults with different types of malignancies were picked up from the attendants of Mansoura University Hospital and Ain Shams University Paediatrics Hospital. Their sera were examined for anti-Toxoplasma IgG and IgM antibodies by the micro-ELISA before and after chemotherapy treatment. Ten normal cross-matched individuals were selected as a control group.

Allopurinol in the treatment of zoonotic cutaneous leishmaniasis.

Twenty male patients with zoonotic cutaneous leishmaniasis were included in this study. Each patient received 1200 mg of allopurinol/day in divided doses for a duration of one month. 80% of patients had an excellent response (cure), however, sometimes leaving mild pigmented or faintly coloured skin i.

Schistosoma mansoni hepatic fibrosis in Syrian golden hamsters: effect of dose and duration of infection as shown by immunohistopathological studies.

In this work, 180 Syrian golden hamsters were infected with Schistosoma mansoni and 30 cross matched for age and sex served as control. Infected hamsters were divided into six main groups according to the number of infected cercariae (20, 50, 100, 150, 200 and 250 cercariae). Each group was sub-divided into 5 subgroups, according to the duration of infection after which animals were sacrificed (4, 6, 8, 12 and 24 weeks).

Inhibition of human eosinophil chemotaxis in vitro by the anti-allergic agent emedastine difumarate.

Emedastine difumarate (emedastine), an anti-allergic agent with anti-histaminic properties, was studied for its effect on human eosinophil chemotaxis induced by platelet activating factor (PAF). Peripheral blood eosinophils (98% purity) were obtained from healthy donors and chemotaxis assay were performed in microchemotaxis chambers. Emedastine showed a significant inhibitory effect on 10(-6) M PAF-induced eosinophil chemotaxis, in dose dependent fashion, at concentrations from 10(-6) to 10(-8) M.

Effect of anti-schistosomal treatment on schistosomal hepatic pathology: an experimental study in Syrian golden hamsters.

Thirty Syrian golden hamsters were infected with Schistosoma mansoni and 10 were used as negative controls. Hamsters were infected by 100 cercariae; 15 were treated by praziquantel in doses of 100 mg/kg at 12, 13, 14 and 15 weeks postinfection, and 15 hamsters were left as positive control. Five from each subgroup were sacrificed at 24, 28 and 32 weeks after infection.

Immunoregulatory effect of substance P in human eosinophil migratory function.

Substance P (SP) is a tachykinin involved in the regulation of inflammatory processes. To investigate a modulatory role of the neuropeptide SP in allergic inflammation, we studied its priming effect on human eosinophil chemotaxis and kinetic responses towards platelet activating factor (PAF) and recombinant human interleukin 5 (rhIL-5). Blood was obtained from normal subjects and eosinophils were separated by Percoll discontinuous density gradient centrifugation.

The helminthic parasites of rodents in Dakahlia Governorate, with reference to their Egyptian helminth fauna.

No doubt, rodents are among the most important reservoirs of zoonotic diseases. This paper aimed to survey the helminth fauna of the different species of rodents in Dakahlia Governorate. Eight species of rodents were encountered in the different centers examined.

Natural Leishmania infections in two stray dogs and two Gerbillus pyramidum in Dakahlia Governorate, Egypt.

In Egypt, zoonotic cutaneaus leishmaniasis (ZCL) and infantile visceral leishmaniasis (I.VL.) have been documented.

Immunization against experimental trichinosis using T. spiralis larvae and hydatid fluid antigens.

Immunization of mice against T. spiralis infection using T. spiralis larval glycoproteins as homogenous antigen and crude hydatid fluid as heterogenous antigen showed a marked reduction in larvae burden and a significant rise of serum IgE in immunized mice infected with T.

Immune response in dogs infected with Ancylostoma duodenale.

The relation between the level of serum immunoglobulins (IgG, IgM, IgA and IgE) percentage of T-lymphocyte and egg counts was studied in dogs infected with Ancylostoma duodenale. The serum IgG levels were significantly high and a marked significance was noticed also in the levels of IgM and IgE. An inverse relationship between the concentration of IgG and egg count and a direct association between the percentage of T-lymphocyte and IgG level was proved.

Visceral leishmaniasis among hypersplenic patients in Dakahlia Governorate, Egypt.

Generally speaking, with rapid international travel, it is very common to diagnose infectious diseases in areas where they were not known before. Nowadays, visceral leishmaniasis (VL) is documented in Egypt mainly in Al Agamy, Alexandria. Another case of infantile visceral leishmaniasis was identified in an adult farmer (unusual host) in Banha.

Histopathological picture of two cases of ectopic fascioliasis in Mansoura, Dakhalia.

Two cases of ectopic fascioliasis were reported. The first case was detected in a haematoma in the anterior abdominal wall in a diabetic patient, the second was in an abscess in the upper part of the thigh. The clinical and laboratory findings were discussed.

Impact of the current National Bilharzia Control Programme on the epidemiology of schistosomiasis mansoni in an Egyptian village.

In a population-based study in the Nile Delta of Egypt, the modified Kato thick smear technique was used to study the epidemiology of Schistosoma mansoni. After 2 years of implementation of the National Bilharzia Control Programme by the Ministry of Health, the general prevalence dropped from 47.2% to 21.

The efficacy of IHAT, IFAT and Dot-ELISA in sero-diagnosis of toxoplasmosis in complicated pregnancies.

Studying of 72 pregnant women having congenital anomalies, stillbirth and repeated abortion of first and second trimesters showed Toxoplasma antibodies with high titre by IFAT and Dot-ELISA. Analysis of the results showed a positive correlation between IFAT and Dot-ELISA but not with IHAT. However, Dot-ELISA is simple, sensitive and specific.

A preliminary study on vaginal trichomonal antigens using CIEP and modified ELISA.

The enzyme linked immunosorbent assay (ELISA) and counter-immunoelectrophoresis (CIEP) were used to detect T. vaginalis antigens in vaginal discharge of 47 infected women and 35 controls. Rabbit antisera raised against T.

Impact of schistosomiasis on patient and graft outcome after kidney transplantation.

In this work the impact of schistosomiasis on kidney transplantation was investigated by comparing two groups of patients, group 1 (Schistosoma-infected cases) and group 2 (control cases). In group 1, schistosomiasis was diagnosed in both donor and recipient in 63 cases, in recipient only in 65 cases, and in donor only in eight cases. Schistosomal infection among kidney transplant recipients was S.

Malabsorption syndrome in patients with cryptosporidiosis.

Out of 130 patients presenting with gastroenteritis, oocysts of Cryptosporidium species were detected in the faecal samples of 10 persons (7.69%). The prevalence of the parasite was higher among rural inhabitants (11.

The effect of the initial inoculum dose and post-infection period on larval dispersal in experimental murine toxocariasis.

The distribution of Toxocara canis larvae throughout the tissues of mice was studied in three groups of fourty mice each using three inocula sizes, (200/500 and 1000 eggs/mice). The results obtained revealed a significant interaction between the duration of infection, the inoculum size and the dispersal rate of larvae through the examined organs of experimented with mice.

Toxocara canis antibodies by counter immuno-electrophoresis.

Counter immunoelectrophoresis was used for anti-toxocaral antibodies in mice experimentally infected with Toxocara canis using adult worm antigen. The test seems to be valuable and gives good information about the infected rate.

Human fascioliasis: a parasitic health problem in Dakahlia Governorate, Egypt.

Fascioliasis has a cosmopolitan distribution and is prevalent in sheep-raising countries. Now, it is an increasingly important parasite of man in the Mediterranean countries. In Dakahlia G.

A case of ectopic fascioliasis in a farmer from Mansoura City, Dakahlia, Egypt.

Human fascioliasis is a new parasitic health problem in Egypt. This paper reports a case of ectopic fascioliasis in the right side of the pleural cavity of a farmer.

Biochemical characterization of Leishmania major isolated from two Egyptian patients.

Leishmania major, the cause of human zoonotic cutaneous leishmaniasis, is a widely distributed parasite in the Old World. Here, we report the isoenzyme characterization of two human isolates obtained from Egyptians who never travelled abroad. The two isolates were L.

Antibodies against some zoonotic parasites in commensal rodents trapped from Dakahlia Governorate, Egypt.

A sero-survey for antibodies against leishmaniasis, toxoplasmosis, amoebiasis and schistosomiasis was carried out among four commensal rodents (R. norvegicus, R. rattus, M.