Protective effects of vitamin D (cholecalciferol) on vancomycin-induced oxidative nephrotoxic damage in rats.

Context: Vancomycin (VCM), an important antibiotic against refractory infections, has been used to treat secondary infections in severe COVID-19 patients. Regrettably, VCM treatment has been associated with nephrotoxicity. Vitamin D can prevent nephrotoxicity through its antioxidant effect.

The Preventive Role of Pioglitazone in Glycerol-Induced Acute Kidney Injury in Rats during Two Different Treatment Periods.

Background: Acute kidney injury is the most life-threatening complication of rhabdomyolysis. Glycerol is commonly used to induce this injury. The aim was to investigate the renoprotective effects of pioglitazone and the possible advantage of administering the drug for a longer period.

Antibacterial Activity of Various Plants Extracts Against Antibiotic-resistant Aeromonas hydrophila.

Background: Aeromonas hydrophila cause one of the most important diseases in fishes and lead to economic losses, and may be contaminated human beings.

Objectives: The current research aimed to investigate the anti-bacterial activity shown by the extracts prepared from different parts of Olea europea, Myrtus communis, Thymus vulgaris, Rosmarinuis officinalis, and Achillea falcata that grow in Syria against A. hydrophila that causes the most dangerous bacterial diseases in fish.