Publications by authors named "Shayna L Vicker"
Free Radic Biol Med
January 2022
Article Synopsis
- Thioredoxins are important enzymes that help reduce disulfide bonds in proteins and defend against oxidative stress.
- Variability in the active site motif of thioredoxins in newly sequenced genomes complicates the identification of functional variants.
- A study created a library of thioredoxin variants to examine how mutations affect their ability to reduce disulfides and protect yeast from oxidative damage, revealing that some mutations were more tolerated than others, particularly in specific regions of the active site.
