Publications by authors named "Shaymaa Ik Al-Juboori"
J Exp Clin Cancer Res
May 2019
Article Synopsis
- Metformin, a common diabetes medication, shows potential for treating advanced breast cancer, but resistance varies among cancer types due to complex signaling pathways.
- Research investigated how metformin interacts with different breast cancer cell lines, particularly focusing on the HER2+ phenotype, and its effects on cell behavior and PYK2 activation.
- Results indicated that HER2+ breast cancer cells are more resistant to metformin compared to other types, revealing a link between this resistance and the activation of the protein PYK2.
