Publications by authors named "Shayena Shah"

Article Synopsis
  • Tyrosine kinase inhibitors (TKIs), especially ibrutinib, are commonly used to treat blood cancers, but there are concerns about arrhythmias associated with these medications.
  • A study analyzed 193 patients on long-term cardiac monitoring, revealing that those on ibrutinib had a significantly higher occurrence of atrial fibrillation and non-sustained ventricular tachycardia compared to those on other TKIs or non-TKI treatments.
  • The findings suggest that 25% of ibrutinib patients had to pause their treatment due to arrhythmias, highlighting the need for careful heart monitoring in patients receiving this type of therapy.
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Background: Atrial fibrillation (AF) affects around 6 million Americans. AF management involves pharmacologic therapy and/or interventional procedures to control rate and rhythm, as well as anticoagulation for stroke prevention. Different populations may respond differently to distinct management strategies.

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