Generic orphan drug substitution: a critical analysis of global practices and Saudi Arabia's perspective.

In an era of cost pressure, substituting generic drugs represents one of the main cost-containment strategies of healthcare systems. Despite the obvious financial benefits, in a minority of cases, substitution may require caution or even be contraindicated. In most jurisdictions, to obtain approval, the bioequivalence of generic products with the brand-name equivalent needs to be shown via bioavailability studies in healthy subjects.

Smart Recognition COVID-19 System to Predict Suspicious Persons Based on Face Features.

The coronavirus (COVID-19) is identified at first in Wuhan in December 2019. The apparition of the COVID-19 virus is widely spread to concern all countries worldwide. The World Health Organization (WHO) on March 11 declare COVID-19 a pandemic.