Publications by authors named "Shay Perchik"

The BNT162b2 mRNA vaccine is highly effective against SARS-CoV-2. However, apprehension exists that variants of concern (VOCs) may evade vaccine protection, due to evidence of reduced neutralization of the VOCs B.1.

View Article and Find Full Text PDF

Background: As mass vaccination campaigns against coronavirus disease 2019 (Covid-19) commence worldwide, vaccine effectiveness needs to be assessed for a range of outcomes across diverse populations in a noncontrolled setting. In this study, data from Israel's largest health care organization were used to evaluate the effectiveness of the BNT162b2 mRNA vaccine.

Methods: All persons who were newly vaccinated during the period from December 20, 2020, to February 1, 2021, were matched to unvaccinated controls in a 1:1 ratio according to demographic and clinical characteristics.

View Article and Find Full Text PDF

Navigation by mammals is believed to rely on a network of neurons in the hippocampal formation, which includes the hippocampus, the medial entorhinal cortex (MEC), and additional nearby regions. Neurons in these regions represent spatial information by tuning to the position, orientation, and speed of the animal in the form of head direction cells, speed cells, grid cells, border cells, and unclassified spatially modulated cells. While the properties of single cells are well studied, little is known about the functional structure of the network in the MEC.

View Article and Find Full Text PDF
Article Synopsis
  • Fish rely on their ability to navigate in space for survival, but details about how their brains represent this navigation are not well understood.
  • Researchers used a wireless neural recording system to study goldfish while they swam freely, focusing on the lateral pallium— a key brain area for spatial memory.
  • They discovered that neurons in this brain region encode important information like environmental edges, fish head direction, swimming speed, and direction of movement, enhancing our understanding of how fish navigate.
View Article and Find Full Text PDF