Heterotaxy syndrome infants are at risk for early shunt failure after Ladd procedure.

Background: Cardiac-specific risks and complications after a Ladd procedure in patients with heterotaxy syndrome (HS) and intestinal rotational anomalies (IRA) are unknown. We sought to (1) describe rates of hospital mortality and early systemic-to-pulmonary (S-P) artery shunt failure after the Ladd procedure in patients with HS and (2) explore risk factors associated with early shunt failure in patients with HS with single ventricle (SV).

Methods: This retrospective study included all Ladd procedures performed from January 1999 to December 2012 in patients with HS at a single center.