Publications by authors named "Shawn W McNeeley"
Purpose: The alpha/beta ratio for prostate cancer is postulated to be between 1 and 3, giving rise to the hypothesis that there may be a therapeutic advantage to hypofractionation. The dosimetry and acute toxicity are described in the first 100 men enrolled in a randomized trial.
Patients And Methods: The trial compares 76 Gy in 38 fractions (Arm I) to 70.
Purpose: To report penile bulb (PB) and corporal bodies (CB) doses during intensity-modulated radiation therapy (IMRT) and permanent (125)I prostate implant alone (BT) for favorable, early stage, clinically localized prostate cancer using computed tomography (CT) and magnetic resonance imaging (MRI) to provide a basis for comparison as the initial report of a comprehensive project to develop erectile tissues sparing techniques.
Methods And Material: Prostate, PB and CB volumes were defined by a fused CT/MRI simulation study performed before treatment in 29 IMRT patients and verification study performed 30 days postimplant in 15 BT patients. The median prescribed prostate dose for the IMRT and BT groups was 74 Gy and 145 Gy, respectively.
Purpose: To report our institution's experience of complications and cosmetic results among patients who underwent modified radical mastectomy followed by reconstruction and radiation therapy (RT).
Methods And Materials: Between 1987 and 2002, 85 patients with breast cancer underwent modified radical mastectomy, breast reconstruction, and postoperative RT. Reconstruction consisted of tissue expander/implant (TE/I) in 50 patients and an autologous transverse rectus abdominis myocutaneous (TRAM) flap in 35 patients.
A method for increased dose conformity and segment reduction for SMLC delivered IMRT treatment of the prostate.
Int J Radiat Oncol Biol Phys
November 2003
Purpose: The focus of this work is to develop a practical planning method that results in increased dose conformity and reduced treatment time for segmental multileaf collimation (sMLC) based intensity-modulated radiation therapy (IMRT) delivery.
Methods And Materials: Additional regions for dose constraint are introduced within the normal tissue during the planning process by designing a series of concentric ellipsoids around the target. A dose gradient is then defined by assigning dose constraints to each concentric region.
Purpose: Despite the wide use of permanent prostate implants for the treatment of early stage prostate cancer, there is no consensus for optimal pre-implant planning guidelines that results in maximal post-implant target coverage. The purpose of this study was to compare post-implant target volume coverage and dosimetry between patients treated before and after Radiation Therapy Oncology Group (RTOG) 98-05 guidelines were adopted using several dosimetric endpoints.
Materials And Methods: Ten consecutively treated patients before the adoption of the RTOG 98-05 planning guidelines were compared with ten consecutively treated patients after implementation of the guidelines.
Purpose: The focus of this work was to compare noncoplanar beam arrangements used for intensity-modulated radiation therapy (IMRT) step-and-shoot delivery to several axial beam arrangements used in the treatment of clinically localized prostate cancer.
Methods And Materials: A 5-field coronal crossfire beam arrangement was developed for IMRT with the objective of improving upon the rectal and bladder dose-volume histograms obtained using 5-, 7-, and 9-field axial beam arrangements. Additionally, a modified 7-field crossfire technique was developed yielding improved dose distributions.