Cell carcinoma of the paranasal sinuses and skull base.

Purpose: To evaluate patients with squamous cell carcinoma of the paranasal sinus and skull base for factors that might predict clinical outcome.

Methods: A multi-institutional 13-year retrospective review of anterior skull base malignancies.

Results: Of 73 patients with anterior skull base malignancies, squamous cell carcinoma was the most prevalent-30 patients or 41%.

Intradermal positivity after negative prick testing for inhalants.

Objective: Examine the incidence of positive intradermal tests after a negative skin prick test for 24 inhalant antigens.

Study Design And Setting: Retrospective study. Charts from patients who underwent modified quantitative testing (MQT) over a 3-year period were reviewed.

Human papillomavirus (HPV) transcripts in malignant inverted papilloma are from integrated HPV DNA.

Objectives: The objectives of the study were to detect human papillomavirus (HPV) sequences in nasal inverted papilloma (IP) lesions and to determine whether HPV is involved in the progression of IP to sinonasal squamous cell carcinoma (SCC).

Study Design: A retrospective study was performed on 14 patients diagnosed with IP within the last 12 years. Three of these 14 patients developed SCC.

Pulmonary involvement in a case of juvenile-onset recurrent respiratory papillomatosis.

Juvenile-onset recurrent respiratory papillomatosis is primarily a disease of children and adolescents. Although most patients experience spontaneous regression at a later age, some patients continue to be affected throughout their lives. We report the case of a 35-year-old woman with a 33-year history of juvenile-onset recurrent respiratory papillomatosis who developed pulmonary dissemination with malignant transformation.