Ablative fractional CO laser vs lyophilized growth factor intralesional injection vs combination of both modalities for striae distensae treatment.

Background: Different studies had evaluated the efficacy of fractional CO laser and platelet-rich plasma (PRP) in treating striae distensae (SD). Lyophilized growth factors (LGF) represent another form of delivering growth factors similar to PRP with a more standardized method. To the best of our knowledge, no previous trials have been reported using LGF in SD.