Publications by authors named "Shaulan Jaime"
Development
December 2005
Article Synopsis
- The left-right (LR) body axis alignment in vertebrates is crucial for body plan organization and is controlled by a structure called the node/organizer.
- Wnt3a plays a significant role in establishing LR asymmetry by activating the Delta/Notch pathway, influencing the expression of left-determining genes like Nodal, and regulating molecular oscillations involved in segmentation.
- Wnt3a acts as a long-range signaling molecule in embryonic development, linking the segmentation clock and body axis elongation while potentially affecting the symmetry-breaking function of cilia in the node.
