Publications by authors named "Shaukat Ali"

Background: The impact of direct and indirect drivers on linear growth and wasting in young children is of public health interest. While the contributions of poverty, maternal education, empowerment and birth weight to early childhood growth are well recognized, the contribution of environmental factors like heat, precipitation, agriculture outputs and food security in comparable datasets is less well established.

Objectives: To investigate the association of length-for-age z-score (LAZ) and weight-for-length z-score (WLZ) with various indicators among children under 2 years of age in Pakistan using representative household level nutrition surveys and ecological datasets.

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Introduction: Inspired by the obstacle avoidance mechanism of goose neck, a theoretical design method of bionic robotic arm was proposed to solve the contradiction between high flexibility and strong bearing capacity in narrow space.

Methods: Taking the goose neck as the test object, a narrow space test environment with a width of 10 cm was built, and a 6 × 4 obstacle matrix was set up, to analyze the maximum value of joint angle, motion rate and trajectory in different target areas.

Results: The test results showed that the goose neck movement has continuity and transmissibility.

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Nowadays, Manganese (Mn) become an unavoidable ingredient in agriculture, medical and manufacturing industries. Manganese deficiency is rare, and even though recurrent exposure to manganese is inevitable for humans, concerns have been voiced regarding public health hazards. This research was designed to evaluate the manganese toxicity and potential protective effects of turmeric in Swiss albino male mice.

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Introduction: Diabetes causes complications like delayed wound healing for a long time. Fibroin, aloe vera, and ginger extracts along with their combinations are used for diabetic wound healing.

Methods: After induction of diabetes, The wound healing effects of fibroin (50 mg/ml), aloe vera gel (50 mg/ml), and ginger extract (30 mg/ml), individually and in combination, were assessed.

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Article Synopsis
  • * Various hepatotoxic substances can disrupt gut flora, leading to increased intestinal permeability and allowing harmful substances to enter the liver, causing damage and inflammation.
  • * Probiotics are emerging as a promising treatment for hepatotoxicity due to their ability to enhance gut health, reduce inflammation, and improve liver function with fewer side effects than traditional treatments.
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Background: Infertility has been observed as one of the major issues in humans, one known risk factor is heavy metals.

Methods: The main focus of the present research was to assess the toxic effect of hexavalent chromium (Cr (VI)) on sperm and its mitigation by Nigella sativa seed extract (NS) and its conjugated silver nanoparticles (NS + NP). In the present study, we administered 1.

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Precipitation extremes have surged in frequency and duration in recent decades, significantly impacting various sectors, including agriculture, water resources, energy, and public health worldwide. Pakistan, being highly susceptible to climate change and extremes, has experienced adverse events in recent times, emphasizing the need for a comprehensive investigation into the relationship between precipitation extremes and crops production. This study focuses on assessing the association between precipitation extremes on crops production, with a particular emphasis on the Punjab province, a crucial region for the country's food production.

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  • During the 2023 soybean growing season in South Dakota, wilting symptoms and blighted leaves were observed in soybean plants, prompting the collection of symptomatic samples for pathogen identification.
  • Researchers used a method involving surface sterilization and incubation on wet filter paper, leading to fungal growth and isolation of a pathogen identified as Fusarium luffae with high genetic similarity to known strains.
  • The pathogenicity of the isolated fungus was assessed through spray inoculations on soybean leaves and plants, indicating its potential impact on soybean crops.
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Diabetes mellitus causes impaired diabetic wounds which is linked to a number of pathological alterations that impede the healing of wounds. In the current research, Swiss albino mice were given alloxan monohydrate to induce diabetes and excision wounds of approximately 6 mm using biopsy punch. The diabetic wounds were treated with various biomaterials including Vachellia nilotica extract (VN), Nigella sativa extract (NS), V.

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Background: Numerous cellular, humoral, and molecular processes are involved in the intricate process of wound healing.

Pharmacological Relevance: Numerous bioactive substances, such as ß-sitosterol, tannic acid, gallic acid, protocatechuic acid, quercetin, ellagic acid, and pyrogallol, along with their pharmacokinetics and bioavailability, have been reviewed. These phytochemicals work together to promote angiogenesis, granulation, collagen synthesis, oxidative balance, extracellular matrix (ECM) formation, cell migration, proliferation, differentiation, and re-epithelialization during wound healing.

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Cardiovascular disease (CVD) is a common cardiac disorder that leads to heart attacks, strokes, and heart failure. It is primarily characterized by conditions that impact the heart and blood arteries, including peripheral artery disease, arrhythmias, atherosclerosis, myocardial ischemia, congenital heart abnormalities, heart failure, rheumatic heart disease, hypertension, and cardiomyopathies. These conditions are mainly effect the heart and blood vessels, causing blockages or weakened pumping, due to severe hereditary and environmental factors.

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Wounds are the common fates in various microbial infections and physical damages including accidents, surgery, and burns. In response, a healthy body with a potent immune system heals that particular site within optimal time by following the coagulation, inflammation, proliferation, and remodeling phenomenon. However, certain malfunctions in the body due to various diseases particularly diabetes and other physiological factors like age, stress, etc.

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Banana Fusarium wilt, caused by Fusarium oxysporum f. sp. cubense tropical race 4 (Foc TR4), is a major disease of banana plants worldwide.

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Objective: The current review is designed to elaborate and reveal the underlying mechanism of sericin and its conjugates of drug delivery during wounds and wound-related issues.

Significance: Wound healing is a combination of different humoral, molecular, and cellular mechanisms. Various natural products exhibit potential in wound healing but among them, sericin, catches much attention of researchers due to its bio-functional properties such as being biodegradable, biocompatible, anti-oxidant, anti-bacterial, photo-protector, anti-inflammatory and moisturizing agent.

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Cancer metabolism has emerged as a potential target for innovative therapeutic approaches in the treatment of cancer. Cancer metabolism has received much attention, particularly in relation to glucose metabolism. It has been observed that human malignancies have high levels of glucose-6-phosphate dehydrogenase (G6PD) activity which is an important enzyme of glucose metabolism.

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Numerous nano-dimensioned materials have been generated as a result of several advancements in nanoscale science such as metallic nanoparticles (mNPs) which have aided in the advancement of related research. As a result, several significant nanoscale materials are being produced commercially. It is expected that in the future, products that are nanoscale, like mNPs, will be useful in daily life.

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Nanotechnology has become a major topic of study, particularly in the medical and health domains. Because nanomedicine has a higher recovery rate than other conventional drugs, it has attracted more attention. Green synthesis is the most efficient and sustainable method of creating nanoparticles.

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In the pediatric population, foreign bodies within the urinary bladder are uncommon, typically resulting from urethral insertion out of curiosity. Other etiologies include sexual assault, iatrogenic factors, or migration from adjacent sites. Symptoms such as urinary retention, dysuria, increased frequency, decreased volume, nocturia, hematuria, painful erections, and pelvic pain are common.

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The diamondback moth (Plutella xylostella), a major threat to crucifers across the globe, has developed resistance against the majority of insecticides enhancing the need for alternate control measures against this pest. Recently cyclosporin C, a secondary metabolite produced by the insect pathogenic fungus Purpeocillium lilacinum, has been reported to induce lethal and sub-lethal effects against P. xylostella.

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Article Synopsis
  • Fusarium head blight (FHB) is a damaging wheat disease that decreases yield and quality, making it critical to develop resistant cultivars, but current phenotyping methods are biased and costly.
  • The study utilized AI-based techniques for accurate estimation of Fusarium-damaged kernels (FDK) and showed that this approach significantly improved predictive ability for deoxynivalenol (DON) in genomic selection models.
  • Additionally, hyperspectral imaging combined with deep learning further refined predictions for DON, indicating that AI and advanced imaging can effectively enhance trait selection in FHB-affected wheat.
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  • * Various agro-waste derived biochars (wheat straw, orange peel, rice husk, and a composite biochar) were tested for their effectiveness at different application rates in reducing bioavailable THMs and health risks.
  • * Results showed that the composite biochar was the most effective in lowering THM uptake and health risks, suggesting it as a safe and eco-friendly amendment for contaminated soils.
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A series of novel Schiff base derivatives (1-28) of 3,4-dihydroxyphenylacetic acid were synthesized in a multi-step reaction. All the synthesized Schiff bases were obtained in high yields and their structures were determined by HNMR, CNMR, and HR-ESI-MS spectroscopy. Except for compounds 22, 26, 27, and 28, all derivatives show excellent to moderate α-glucosidase inhibition.

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The demand for identification of maize varieties has increased dramatically due to the phenomenon of mixed seeds and inferior varieties pretending to be high-quality varieties continuing to occur. It is urgent to solve the problem of efficient and accurate identification of maize varieties. A hyperspectral image acquisition system was used to acquire images of maize seeds.

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The present study incorporated an environment-friendly and cost-efficient green synthesis method for fabricating zinc oxide nanoparticles (ZnO-NPs) using various parts (leaves, buds, and flowers) of Bauhinia Variegate Linn. UV-Spectrophotometric analysis was used to confirm the synthesis of ZnO-NPs, which showed an absorption band within 360-380 nm range. Further techniques like FT-IR spectroscopy and (SEM) scanning electron microscopy equipped with a novel EDX were also included to confirm the synthesis, size, and shape of ZnO-NPs.

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A million ton of cotton fabric is wasted during cutting process in garment industry as well as in textile dyeing industry due to faulty dyeing. Color stripping of cotton fabric has become a significant challenge in the textile industry because the harsh chemicals used in chemical stripping processes affects the quality of fabric very badly. Conventional stripping methods lead with severe effects due to prolonged treatment time and high chemical concentrations.

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