Publications by authors named "Shashikant L Juvekar"
Leiomyosarcomas of vascular origin are very rare tumors, predominantly affecting the inferior vena cava (IVC). Although vascular leiomyosarcomas are slow-growing, their non-specific and late presentation results in delayed diagnosis which portends a very poor prognosis. Here we report a case of a 24-year-old man who presented with abdominal pain since 15 days and was found to have unresectable metastatic leiomyosarcoma of the inferior vena cava at initial diagnosis.
View Article and Find Full Text PDFIntroduction: Primary bone and soft tissue sarcomas are rare, but diagnostically and therapeutically challenging group of tumors, requiring multidisciplinary management. There are limited documented studies from multidisciplinary teams , in the form of comprehensive analysis of these tumors, from our country. This study is an analysis of cases of osteosarcomas, Ewing sarcomas (ESs), chondrosarcomas (CSs), and soft-tissue sarcomas (STSs), registered at our institution during 2012.
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- Chemoradiation with cisplatin 100 mg/m every 3 weeks is the standard treatment for locally advanced head and neck squamous cell cancer (LAHNSCC), while weekly low-dose cisplatin (30 mg/m) is sometimes used due to lower toxicity and convenience, despite lacking strong evidence on its effectiveness.
- A phase III trial with 300 patients compared the two dosing schedules, focusing on outcomes like locoregional control (LRC), toxicity, and survival rates; results showed that the 3-week regimen had better LRC (73.1% vs 58.5%) but also produced more severe side effects.
- Despite lower toxicity with the once-a-week regimen, the trial indicated that the
Giant cell tumor of bone (GCTB) is mostly a benign tumor, but associated with recurrences and metastasis. Lately, denosumab is being utilized in the treatment of certain GCTBs. Twenty-seven tumors, analyzed in the present study, occurred in 16 males and 11 females (M: F = 1.
View Article and Find Full Text PDFPurpose: To study the impact of multiparametric MRI and (18)F-FDG-PET on the outcome of children with diffuse intrinsic pontine gliomas (DIPG).
Materials And Methods: Imaging data from a phase-II prospective therapeutic study in children with newly diagnosed DIPG were considered for evaluation. They included baseline MRI with contrast enhancement before treatment.