In Situ Measuring Partition Coefficient at Intact Nanoemulsions: A New Application of Single-Entity Electrochemistry.

We report a new application of the single-entity electrochemistry (SEE) to in situ measure a partition coefficient at intact nanoemulsions (NEs). The partition coefficient at intact NEs is the most crucial physicochemical property to determine the uptake of delivery molecules inside NEs. It, however, has not been unequivocally elucidated by currently existing techniques based on ex situ measurements.

Towards ultralow detection limits of aromatic toxicants in water using pluronic nanoemulsions and single-entity electrochemistry.

We demonstrate a new electroanalytical technique using nanoemulsions (NEs) as a nanoextractor combined with single entity electrochemistry (SEE) to separate, preconcentrate analytes from bulk media, and even detect them in situ, enabling ultratrace level analysis. This approach is based on our hypothesis that the custom-designed NEs would enable to effectively scavenge compounds from bulk media. Herein, we use Pluronic F-127 functionalized NEs to extract, preconcentrate target analytes e.

Single-Entity Electrochemistry of Nanoemulsion: The Nanostructural Effect on Its Electrochemical Behavior.

New electrochemical approaches have been applied to investigate nanoemulsions (NEs) for their nanostructures and the relevant electrochemical activity by single-entity electrochemistry (SEE). Herein, we make highly monodisperse NEs with ∼40 nm diameter, composed of biocompatible surfactants, castor oil as plasticizers, and ion exchangers. Dynamic light scattering (DLS) measurements with periodically varying surfactant to oil ratios provide us with a structural implication about uneven distributions of incorporating components inside NEs.