B-Map: a fuzzy-based model to detect foreign objects in a brain.

To cope up with the medical complications, scientists and physicians rely more on digitized historical evidence. It helps them to identify the disease and to develop new drugs and strategies. The authors have designed a model called B-Map.

Enhancement in the Neuroprotective Power of Riluzole Against Cerebral Ischemia Using a Brain Targeted Drug Delivery Vehicle.

Riluzole is the only available drug for motor neuron diseases quite well-known for its neuroprotective activity. But its poor aqueous solubility, short half-life with some side-effects at higher concentration poses a limitation to its use as a therapeutic agent. The present study was performed to investigate the therapeutic potential of nanoriluzole (NR), i.

Nanoparticle Based Delivery of Quercetin for the Treatment of Carbon Tetrachloride Mediated Liver Cirrhosis in Rats.

Liver fibrosis is the common response to chronic liver injury and ultimately leads to cirrhosis. There is a pressing need in the pharmaceutical industry to develop efficient well-targeted drug delivery systems, which are lacking to date. This study was designed to investigate the efficacy of a nanoquercetin NQ; i.

Nanothymoquinone, a novel hepatotargeted delivery system for treating CCl mediated hepatotoxicity in rats.

Thymoquinone (TQ) is the major active principle of Nigella sativa (N. sativa) which is widely being used as a hepatoprotective agent nowadays. However, toxicity at high doses with poor water solubility limit its usage as a therapeutic agent.