Publications by authors named "Shashank R Gupta"

Purpose: To evaluate the anatomic and visual outcomes and safety profile of initial Indian eyes with neovascular age-related macular degeneration (nAMD) treated with intravitreal injection (IVI) of brolucizumab.

Methods: This retrospective multicentric, real-world study enrolled consecutive eyes with nAMD that were treated with IVI brolucizumab after it was launched in India in October 2020. Data collected for each eye included best-corrected visual acuity (BCVA), central subfield thickness (CSFT), subretinal fluid (SRF), and intraretinal fluid (IRF) status at 6, 12, and 24 months follow-up.

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Purpose: The aim of this study was to present the outcomes of the 2018 and 2020 Vitreo-retinal Society of India (VRSI) biosimilars of anti-vascular endothelial growth factor (VEGF) (VIBE) surveys.

Methods: An online survey of members of VRSI was conducted in July 2018 and January 2020 regarding their practice-patterns on anti-VEGF biosimilars pertaining to safety, efficacy, pricing, and need for enhanced clinical trials before regulatory approval.

Results: In 2018, 112 VRSI members participated, whereas in 2020, 98 society members participated.

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Purpose: To describe a surgical technique for salvaging recurrent exposure of scleral buckle.

Methods: A patient, treated for rhegmatogenous retinal detachment with scleral buckle, presented with exposed uninfected buckle 3 weeks after the initial surgery. We tried to cover the exposure twice with conjunctivoplasty and once with scleral patch graft with amniotic membrane transplantation, but each one of them failed.

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Purpose: We report iatrogenic occurrence of a macular tractional retinal detachment with macular hole in nonperfused hemiretinal vein occlusion and describe its management with vitrectomy, without internal limiting membrane peeling.

Methods: A 40-year-old man with diabetes was treated with scatter photocoagulation for a unilateral nonperfused hemiretinal vein occlusion with a florid neovascularization at optic disk and best-corrected visual acuity of 20/200. A month later, he developed an extensive tractional detachment of the posterior pole with a macular hole, with further drop in vision to hand motions.

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Purpose: To describe the natural course of Type 2 idiopathic macular telangiectasia in terms of visual outcomes, causes of visual loss, and incidence of subretinal neovascular membranes (SRNV).

Methods: This retrospective observational case series consisted of chart review of 104 outpatients (203 eyes; 66 women, 38 men) who were diagnosed to have Type 2 idiopathic macular telangiectasia by clinical examination and fluorescein angiography between January 2000 and December 2008. Visual and anatomic outcomes were analyzed during a minimum follow-up of 1 year.

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