Publications by authors named "Sharyn M Leis"
Article Synopsis
- The study investigates whether fecal bacteriotherapy can create lasting positive changes in the gut microbiota of patients with related disorders.
- Earlier research has shown that introducing healthy microbiota through fecal suspension can treat conditions like Clostridium difficile infection, but there's been no evidence of long-term effects until now.
- Results indicated that patients retained a significant presence of bacteria from the healthy donor up to 24 weeks post-treatment, suggesting that this therapy could be a viable, long-lasting treatment option for gastrointestinal issues.
The intestinal flora may play a key role in the pathogenesis of certain gastrointestinal (GI) diseases. Components of bowel flora such as Lactobacillus acidophilus and Bifidobacterium bifidus have long been used empirically as therapeutic agents for GI disorders. More complex combinations of probiotics for therapeutic bacteriotherapy have also recently become available, however the most elaborate mix of human-derived probiotic bacteria is, by definition, the entire fecal flora.
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