Identification and characterization of proteins involved in nuclear organization using Drosophila GFP protein trap lines.

Background: Strains from a collection of Drosophila GFP protein trap lines express GFP in the normal tissues where the endogenous protein is present. This collection can be used to screen for proteins distributed in the nucleus in a non-uniform pattern.

Methodology/principal Findings: We analyzed four lines that show peripheral or punctate nuclear staining.