Publications by authors named "Sharon Reale"

Postpartum hemorrhage (PPH) is the leading cause of maternal mortality worldwide, and mitigating it is a global health priority. In this review, we discuss the measurement, assessment, and treatment of PPH. We review different methods of quantifying blood loss, including gravimetry, calibrated drapes and canisters, and colorimetric techniques.

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Background: Large language models (LLMs), of which ChatGPT is the most well known, are now available to patients to seek medical advice in various languages. However, the accuracy of the information utilized to train these models remains unknown.

Methods: Ten commonly asked questions regarding labor epidurals were translated from English to Spanish, and all 20 questions were entered into ChatGPT version 3.

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Background: Patients are increasingly using artificial intelligence (AI) chatbots to seek answers to medical queries.

Methods: Ten frequently asked questions in anaesthesia were posed to three AI chatbots: ChatGPT4 (OpenAI), Bard (Google), and Bing Chat (Microsoft). Each chatbot's answers were evaluated in a randomised, blinded order by five residency programme directors from 15 medical institutions in the USA.

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Viscoelastic hemostatic assays are point-of-care devices that assess coagulation and fibrinolysis in whole blood samples. These technologies provide numeric and visual information of clot initiation, clot strength, and clot lysis under low-shear conditions, and have been used in a variety of clinical settings and subpopulations, including trauma, cardiac surgery, and obstetrics. Emerging data indicate that these devices are useful for detecting important coagulation defects during major postpartum hemorrhage (especially low plasma fibrinogen concentration [hypofibrinogenemia]) and informing clinical decision-making for blood product use.

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Article Synopsis
  • The study investigates why some women experience more pain and use more opioids after cesarean delivery, aiming for better personalized pain management practices.
  • It compares three different questionnaires (a 3-item, a longer 58-item, and a 19-item) to see which can best explain variations in psychosocial factors affecting pain and opioid use.
  • Results show that both the brief and long questionnaire models are more effective than the 3-item model, revealing important factors like surgical anxiety and expected pain medication needs that influence postoperative pain and opioid consumption.
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Article Synopsis
  • The study aimed to provide updated estimates of difficult and failed intubation rates in women undergoing cesarean delivery with general anesthesia, addressing limitations of previous smaller studies.
  • The research analyzed data from nearly 14,800 cesarean deliveries (2004-2019) and found a difficult intubation rate of 1 in 49 and a failed intubation rate of 1 in 808, identifying key risk factors such as high body mass index and certain anatomical limitations.
  • The findings highlight the importance of understanding risk factors to improve patient safety and outcomes during cesarean deliveries requiring general anesthesia.
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Background: Although Von Willebrand disease (vWD) is the most common heritable bleeding disorder, there are limited reports regarding the safety of neuraxial anesthesia in the obstetric population and no definitive guidelines specifying recommended pretreatment or therapies for patients with vWD. The aim of this study is to describe the anesthetic management of pregnant patients with vWD at a large tertiary-care center.

Methods: In this retrospective analysis, the study population was identified from vWD patients evaluated by our high-risk obstetric anesthesia consultation service and by diagnosis codes from our institutional research database registry.

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Background: While studies from large cities affected by coronavirus disease 2019 (COVID-19) have reported on the prevalence of SARS-CoV-2 in the context of universal testing during admission for delivery, the patient demographic, social and clinical factors associated with SARS-CoV-2 infection in pregnant women are not fully understood.

Objective: To evaluate the epidemiological factors associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in women admitted for labour and delivery, in the context of universal screening at four Boston-area hospitals.

Methods: In this prospective cohort study, we reviewed the health records of all women admitted for labour and delivery at four hospitals from the largest health system in Massachusetts between 19 April 2020 and 27 June 2020.

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This case-control study estimates the risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among pregnant women making antenatal visits to 4 Boston, Massachusetts, area hospitals during April-June 2020 vs uninfected controls matched on gestational age.

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Background: There have been many advances in obstetric anesthesiology in the past 2 decades. We sought to create a list of highly influential publications in the field using the Delphi method among a group of obstetric anesthesiology experts to create an important educational, clinical, and research resource.

Methods: Experts in the field, defined as obstetric anesthesiologists selected to present the Gerard W.

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Background: Postpartum hemorrhage (PPH) is a leading cause of maternal mortality worldwide. While volumetric and gravimetric blood loss measurement techniques have been shown to increase PPH detection compared to visual estimation of blood loss (vBL), a combination of these methods has not been evaluated. The primary aim of this study was to compare the change in odds of PPH detection after vaginal delivery (VD; the intervention series) versus cesarean delivery (CD; the control series) before versus after implementation of a device (Triton L&D, Gauss Surgical, Inc, Los Altos, CA) that combines gravimetric and volumetric estimation of blood loss (tBL).

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Postpartum hemorrhage (PPH) is a leading cause of morbidity and mortality in the United States; its prevalence increased during the 1990s-2000s. The purpose of this study was to reevaluate trends in PPH using the National Inpatient Sample. From 2010 to 2014, the prevalence of PPH increased from 2.

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