Publications by authors named "Sharon Kay Valero"
Globally, about 50% of liver cancer originates as a result of long term infection with hepatitis B virus (HBV), and some genotypes and mutations have been associated with an increased severity of infection. The aim of this study was to evaluate the genetic diversity of HBV in patients from Venezuela, with chronic infection, cirrhosis and hepatocellular carcinoma (HCC) and to compare the occurrence of mutations in all patient groups. Samples from patients with different pathologies of the liver, associated with HBV infection, were collected.
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- Abdominal ultrasound is effective for diagnosing periportal fibrosis and assessing liver health in Schistosoma mansoni patients.
- Evaluation of WHO's ultrasound methods showed that 28.2% of patients experienced complete reversal of periportal lesions after praziquantel treatment over 3-5 years, while 5.1% saw disease progression.
- Findings indicate that initial improvements in liver health are shown by reduced periportal thickening, but inconsistencies arise in patients with advanced disease, and no clear link exists between disease progression and patient demographics or infection severity.