Publications by authors named "Sharon Ellender"
Article Synopsis
- The LeucoPatch device is designed to enhance wound healing by using a patient's own blood components (leucocytes, platelets, and fibrin) without any added reagents, targeted at hard-to-heal foot ulcers in diabetic patients.
- A large-scale, international trial was conducted across 32 diabetic foot clinics in the UK, Denmark, and Sweden, comparing standard care to care with weekly application of LeucoPatch after a initial 4-week observation period.
- Results showed that 34% of ulcers healed with LeucoPatch treatment compared to 22% with standard care, indicating a statistically significant improvement in healing and a faster recovery time, with similar rates of adverse events between both treatment groups.
Background: Poststroke cognitive impairment is common and identification of prognostic factors associated with it and its relationship with other functional outcomes may help in developing preventative strategies.
Methods: Previously independent patients with acute stroke, enrolled into the ongoing "Efficacy of Nitric Oxide in Stroke" trial, were assessed by telephone on day 90 for cognitive impairment using modified versions of "Mini Mental State Examination" (MMSE-M) and "Telephone Instrument for Cognitive Status" (TICS-M) scales and category fluency. The relationship of cognitive impairment with baseline prognostic factors and other functional outcomes at day 90 were studied.
Interventions for dysphagia and nutritional support in acute and subacute stroke.
Cochrane Database Syst Rev
October 2012
Background: Dysphagia (swallowing problems) are common after stroke and can cause chest infection and malnutrition. Dysphagic, and malnourished, stroke patients have a poorer outcome.
Objectives: To assess the effectiveness of interventions for the treatment of dysphagia (swallowing therapy), and nutritional and fluid supplementation, in patients with acute and subacute (within six months from onset) stroke.