Invest Ophthalmol Vis Sci
July 2009
Purpose: To investigate the concentration and bioavailability of ciprofloxacin and teicoplanin in the cornea.
Methods: A biological assay was developed with corneal tissue used as a carrier for the antimicrobial. Concentration and biological activity were determined with a chemical assay and zone of inhibition (ZOI) around corneal samples with epithelial and endothelial surfaces in contact with the indicator organism.