Publications by authors named "Sharon A Perlman"
Complications associated with bacitracin powder in surgical wounds.
J Neurosurg Pediatr
December 2015
Article Synopsis
- Renewed interest in using concentrated bacitracin powder during surgical procedures has emerged to reduce infection rates, particularly in pediatric shunt surgeries.
- A retrospective analysis of 597 pediatric patients from 2001 to 2013 was conducted to evaluate bacitracin's safety, focusing on complications like anaphylaxis, wound healing issues, and renal dysfunction.
- Results showed that bacitracin powder did not lead to anaphylaxis or increased wound breakdown compared to control, indicating that its application may be safe and effective in reducing infections without significant complications.
An intradural somatic-to-autonomic anastomosis, or Xiao procedure, has been described to create a "skin-CNS-bladder" reflex that improves bladder and bowel function in patients with neurogenic bladder and bowel dysfunction. The authors present their experience with a 10-year-old boy with chronic neurogenic bladder and bowel dysfunction related to spinal cord injury who underwent the Xiao procedure. After undergoing a left L-5 ventral root to left S2-3 intradural anastomosis, the patient reported that his bladder and bowel dysfunction improved between 6 and 12 months.
View Article and Find Full Text PDFBackground: Hypophosphatasia (HPP) is a rare, heritable, metabolic bone disease due to deficient activity of the tissue-nonspecific isoenzyme of alkaline phosphatase. The infantile form features severe rickets often causing death in the first year of life from respiratory complications. There is no established medical treatment.
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