Publications by authors named "Sharna S"
Methanol-to-hydrocarbons (MTH) process has been considered one of the most practical approaches for producing value-added products from methanol. However, the commonly used zeolite catalysts suffer from rapid deactivation due to coke deposition and require regular regeneration treatments. We demonstrate that low-melting-point metals, such as Ga, can effectively promote more stable methanol conversion in the MTH process by slowing coke deposition and facilitating the desorption of carbonaceous species from the zeolite.
View Article and Find Full Text PDFThe Emerging Role of the Gut-Brain-Microbiota Axis in Neurodevelopmental Disorders.
Adv Exp Med Biol
January 2023
Autism spectrum disorder (ASD; autism) is a prevalent neurodevelopmental disorder associated with changes in gut-brain axis communication. Gastrointestinal (GI) symptoms are experienced by a large proportion of individuals diagnosed with autism. Several mutations associated with autism modify cellular communication via neuronal synapses.
View Article and Find Full Text PDFIndividuals diagnosed with neurodevelopmental conditions such as autism spectrum disorder (ASD; autism) often experience tissue inflammation as well as gastrointestinal dysfunction, yet their underlying causes remain poorly characterised. Notably, the largest components of the body's immune system, including gut-associated lymphoid tissue (GALT), lie within the gastrointestinal tract. A major constituent of GALT in humans comprises secretory lymphoid aggregates known as Peyer's patches that sense and combat constant exposure to pathogens and infectious agents.
View Article and Find Full Text PDFArticle Synopsis
- High-entropy-alloy (HEA) nanoparticles show promise for catalysis and energy applications, but creating complex structures without issues like demixing is challenging.
- * A new soft-chemistry method using spray-drying and polymer latex beads allows for the fabrication of ordered macro- and mesoporous HEA materials with high surface area and thermal stability.
- * This environmentally friendly process is scalable and can potentially be adapted for other HEA materials, enhancing their catalytic performance, particularly for CO oxidation.
Article Synopsis
- The research highlights the limited understanding of copper nanoparticles' oxidation and reduction processes at the nanoscale, which are often based on bulk or thin film studies.
- The study employs in situ Scanning Transmission Electron Microscopy to observe how copper nanoparticles behave under oxidative and reductive conditions at high temperatures (150 °C to 900 °C) and low pressure (0.5 atm), revealing significant differences in nanoparticle mobility and structural changes based on initial size and temperature.
- Results indicate that oxidation leads to the formation of hollow oxide shells and subsequent collapse into compact nanoparticles, while reduction is influenced by the starting phase morphology, providing insights for improved material design in industrial applications.
The intrinsic nervous system of the gut interacts with the gut-associated lymphoid tissue (GALT) bidirectional neuroimmune interactions. The caecum is an understudied region of the gastrointestinal (GI) tract that houses a large supply of microbes and is involved in generating immune responses. The caecal patch is a lymphoid aggregate located within the caecum that regulates microbial content and immune responses.
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