Background: To evaluate the efficacy of the smear layer removal with Fumaric acid when used in combination with new generation files Hyflex Electrical Discharge Machining (HEDM) file, Neoendo file, and Blueflex file.
Materials And Methods: Sixty extracted mandibular premolars with single-canal were selected for this study. Radiographs were taken to confirm the presence of single canal and absence of any type of calcifications, resorption, cracks, and fractures.